High-risk mucosal HPV types associated with squamous cell carcinoma on the nose tip in an immunocompetent young man.

Anais Brasileiros De Dermatologia
Camila Fátima Biancardi GavioliWalmar Roncalli Pereira de Oliveira

Abstract

The oncogenic role of high-risk HPV in anogenital, head and neck, and cervical cancer is well recognized, but not in skin cancer in the general population. Some authors have demonstrated their appearance mainly on the hands and feet, particularly in the area of the nail bed, which could be due to contamination with HPV types from anogenital regions. Here, we describe a case of genital HPV associated with SCC on the nose tip in an immunocompetent young man, which was confirmed by histopathological findings and in situ hybridization. The importance of this report is to highlight the potential role of HPV in the etiology of skin cancer in an immunocompetent individual.

References

Nov 15, 2008·Gynecologic Oncology·Renata De Marchi TrigliaLiliana A Lucci De Angelo Andrade
Feb 15, 2011·Journal of the American Academy of Dermatology·Catherine RiddelVal Thomas
Mar 19, 2014·Journal of the American Academy of Dermatology·Jennifer WangSarah Tuttleton Arron
Mar 1, 2015·Virology·Peter M Howley, Herbert J Pfister

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Methods Mentioned

BETA
PCR

Related Concepts

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Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

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