High-sensitivity C-reactive protein and mean platelet volume as predictive values after percutaneous coronary intervention for long-term clinical outcomes: a comparable and additive study

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
Ae Ran MoonTae-Hyoung Kim

Abstract

This study was designed to establish the relationship of high-sensitivity C-reactive protein (hsCRP) and mean platelet volume (MPV) with the development of adverse outcomes after percutaneous coronary intervention (PCI). hsCRP levels and MPV were analysed in 372 patients who underwent PCI, with the primary endpoint as major adverse cardiac and cerebrovascular events (MACCE): a composite of cardiac death, myocardial infarction (MI), target vessel revascularization (TVR), ischemic stroke and stent thrombosis. During the follow-up period (mean, 25.8 months), there were 21 cardiac deaths, 10 MIs including four stent thrombosis events, seven ischemic strokes and 29 TVRs. The hsCRP cut-off level was set at 0.31 mg/dl using the receiver operating characteristic curve to differentiate between the groups with and without MACCE. The MPV cut-off level was set at 8.00 fl by the receiver operating characteristic curve to differentiate between the groups with and without MACCE. A Kaplan-Meier analysis revealed that the high hsCRP group (≥0.31 mg/dl) had a significantly higher cardiac death and MACCE rate than the low hsCRP group (<0.31 mg/dl), and the high MPV group (>8.00 fl) had a significantly higher cardiac death and MACCE rate than the ...Continue Reading

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Citations

Nov 4, 2016·The Korean Journal of Internal Medicine·Dong-Hyun ChoiHeesang Song
May 29, 2016·Vascular·Huseyin SaskinUğur C Koçoğulları
Apr 19, 2018·Critical Reviews in Clinical Laboratory Sciences·Konstantinos MakrisGeorgios Tsivgoulis
Jun 11, 2020·Journal of the American Heart Association·Adebamike A OshunbadeMichael E Hall
Apr 22, 2020·Proceedings·Somedeb BallKenneth Nugent

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Methods Mentioned

BETA
blood-drawing

Software Mentioned

MedCalc
SPSS

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