High seroprevelance of West Nile virus antibodies observed in horses from southwestern Nigeria

Vector Borne and Zoonotic Diseases
Waidi Folorunso SuleNicholas Johnson

Abstract

To investigate exposure of Nigerian horses to West Nile virus (WNV), we determined the seroprevalence rate of anti-WNV antibody in a cohort of 145 horses. Serum samples were collected from three locations in southwestern Nigeria between October, 2011, and July, 2012. The horses were asymptomatic and unvaccinated against WNV at the time of sampling. All sera were tested using a competition enzyme-linked immmunosorbent assay (ELISA) and by an immunoglobulin M (IgM)-specific ELISA. High rates of anti-WNV antibody prevalence were observed in all locations with a mean level of 90.3% (95% confidence interval 84.3-94.6%). None of the horses had detectable anti-WNV IgM. This is the first ELISA-based report of WNV seroprevalence in Nigerian horses and suggests that WNV is enzootic in the study areas, indicating a potential risk of infection in humans and animals.

References

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Citations

May 23, 2018·Transactions of the Royal Society of Tropical Medicine and Hygiene·Istifanus J WaziriPatrick Nguku
Jun 9, 2018·Parasites & Vectors·Daniel OluwayeluOyewale Tomori
Jul 15, 2018·Parasites & Vectors·Waidi F SuleNicholas Johnson
Nov 8, 2018·Zoonoses and Public Health·Maged G HemidaMalik Peiris
Oct 15, 2020·Transactions of the Royal Society of Tropical Medicine and Hygiene·Idoko Sunday IdokoAmir Steinman
Jun 3, 2021·Animal Health Research Reviews·Luís DionísioAna I Faustino-Rocha
May 28, 2021·One Health·Chikwe IhekweazuUNKNOWN Nigeria Zoonotic Diseases Prioritization Group

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Methods Mentioned

BETA
Enzyme-Linked Immunosorbent Assay

Software Mentioned

SPSS

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