High serum ferritin level is an independent risk factor for metabolic syndrome in a Chinese male cohort population

Diabetology & Metabolic Syndrome
Qin TangZengnan Mo

Abstract

Elevated serum ferritin levels have been reported to contribute to metabolic syndrome (MetS). We examined the association of serum ferritin levels with the development of MetS in a representative sample of Chinese male adult population. The data came from the 2009-2013 Fangchenggang Area Males Health and Examination Survey (FAMHES). We combined a cross-sectional study of 2417 males and a longitudinal study of 857 males who participated in the FAMHES. The serum ferritin level of MetS was higher than that of nonMetS (median and percentiles 25-75: 447.4 (294.1-612.4) vs. 302.4 (215.0-435.8) ng/ml, p < 0.01). A positive correlation between ferritin concentrations and blood pressure (Systolic BP: R = 0.110, Diastolic BP: R = 0.158), waist circumference (R = 0.333), fasting glucose (R = 0.089), triglyceride (R = 0.315) and low high-density lipoprotein cholesterol (R = 0.130) was significant (all p < 0.001). Compared with the level of ferritin in the group with no MetS component, the group with all five MetS components had a higher ferritin level (554.7 (340.1-606.4) vs. 274.2 (198.2-384.4) ng/ml). The odd radio (OR) was higher for MetS in the highest ferritin quartile (OR = 2.29, 95% CI = 1.47-3.54) compared with the lowest ferritin ...Continue Reading

References

Dec 23, 1999·The New England Journal of Medicine·N C Andrews
Jun 30, 2000·American Heart Journal·L R ZacharskiL M Schwartz
Feb 13, 2001·European Journal of Haematology·N MilmanP Bjerregaard
Aug 13, 2002·Journal of Hypertension·Alberto PipernoGiuseppe Mancia
Jan 11, 2003·Blood·James D CookBarry S Skikne
Aug 6, 2003·Medicine and Science in Sports and Exercise·Cora L CraigPekka Oja
Sep 29, 2004·Diabetes Care·Megan JehnEliseo Guallar
Aug 17, 2005·Molecular Aspects of Medicine·Susana Puntarulo
Apr 11, 2007·Archives of Internal Medicine·Emily L HarrisPaul C Adams
May 27, 2008·Biochimica Et Biophysica Acta·Swapnil N RajpathakFrank B Hu
Sep 18, 2008·The Journal of Clinical Endocrinology and Metabolism·Liang SunXu Lin
Nov 17, 2009·Metabolism: Clinical and Experimental·Rocio Mateo-GallegoFernando Civeira
Jan 30, 2010·Lancet·Robert H EckelPaul Z Zimmet
Sep 6, 2011·Biological Trace Element Research·Milton Fabian Suárez-OrtegónCecilia Aguilar-de Plata
Jan 27, 2012·American Journal of Hypertension·Mee Kyoung KimKi Won Oh
Oct 23, 2012·Cancer Letters·Kousuke IshinoHitoshi Nakagama
Jan 7, 2014·PloS One·Susan J Fairweather-TaitAlexander J Macgregor
Mar 13, 2014·International Journal of Environmental Research and Public Health·Yongqiang LiHequn Zou
Jun 3, 2014·BMC Public Health·Victoria Abril-UlloaVictoria Arija
Jun 27, 2014·Indian Journal of Clinical Biochemistry : IJCB·Chintana SengsukSurapon Tangvarasittichai

❮ Previous
Next ❯

Citations

Jul 19, 2016·Journal of Diabetes and Its Complications·Ling ChenLinong Ji
Mar 18, 2020·Food Science & Nutrition·Meichen WangYumei Zhang

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.