High Short-Term Blood Pressure Variability Predicts Long-Term Cardiovascular Mortality in Untreated Hypertensives But Not in Normotensives

American Journal of Hypertension
Pai-Feng HsuChen-Huan Chen

Abstract

The prognostic value of the short-term blood pressure variability (BPV) from the 24-hour ambulatory blood pressure monitoring (ABPM) remains controversial. The present study aimed to investigate the long-term prognostic value of a high BPV in normotensive and hypertensive subjects from a community-based population. A cohort of 624 normotensive and 633 untreated hypertensive Taiwanese participants (overall 669 men, aged 30-79 years) with baseline ABPM and 20-year all-cause and cardiovascular mortality data was drawn from a community-based survey. BPV was assessed by the read-to-read average real variability of the 24-hour diastolic and systolic blood pressure (SBP) (ARVd and ARVs, respectively). In Cox proportional hazards analysis, ARVd predicted cardiovascular mortality independently of office SBP (hazard ratios (HRs) and 95% confidence intervals (CIs) per 1 SD: 1.31 (1.10-1.55), respectively, bivariate analysis), 24-hour SBP (HR: 1.19, 95% CI: 1.00-1.43), and conventional risk factors (age, sex, smoking, total cholesterol, high-density lipoprotein cholesterol, and fasting blood glucose, HR: 1.40, 95% CI: 1.18-1.67). In subjects with hypertension, a high vs. low ARVd (median: 8.8mm Hg) significantly predicted cardiovascular mo...Continue Reading

References

May 19, 2000·International Journal of Epidemiology·T H LuM C Chou
Oct 1, 2003·Blood Pressure Monitoring·Gianfranco ParatiGiuseppe Mancia
Feb 18, 2005·Journal of Hypertension·Luis MenaTulio Sulbarán
Dec 22, 2006·The New England Journal of Medicine·Thomas J WangRamachandran S Vasan
Jun 6, 2009·American Journal of Hypertension·Sante D PierdomenicoFranco Cuccurullo
Mar 10, 2010·Hypertension·Tine W HansenUNKNOWN International Database on Ambulatory Blood Pressure in Relation to Cardiovascular Outcomes Investigators
Mar 17, 2010·Lancet Neurology·Peter M RothwellUNKNOWN ASCOT-BPLA and MRC Trial Investigators
Feb 13, 2013·Nature Reviews. Cardiology·Gianfranco ParatiGrzegorz Bilo
Oct 17, 2014·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kei AsayamaJan A Staessen
Dec 31, 2014·Journal of the Chinese Medical Association : JCMA·Chern-En ChiangShing-Jong Lin

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Citations

Aug 24, 2017·The Journal of Clinical Hypertension·Satoshi HoshideUNKNOWN Characteristics On the ManagEment of Hypertension in Asia - Morning Hypertension Discussion Group (COME Asia MHDG)
Oct 21, 2017·Journal of the American Heart Association·Luis J MenaGladys E Maestre
Nov 30, 2019·Future Cardiology·Robert P Blankfield
Sep 13, 2019·European Journal of Preventive Cardiology·Grzegorz BiloGianfranco Parati
Dec 10, 2019·The Journal of Clinical Hypertension·Kazuomi KarioJi-Guang Wang
May 23, 2019·Blood Pressure Monitoring·Francesca CoccinaSante D Pierdomenico
Dec 14, 2018·The Journal of Clinical Hypertension·Guru P SogunuruUNKNOWN HOPE Asia Network
Sep 19, 2019·The Journal of Clinical Hypertension·Kazuomi KarioJi-Guang Wang
Dec 16, 2020·The Journal of Clinical Hypertension·Kazuomi KarioJi-Guang Wang
Feb 6, 2021·The Journal of Clinical Hypertension·Cesare CuspidiMarijana Tadic
Feb 27, 2021·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Lorenza ScottiAntonella Zambon
Jan 6, 2021·Journal of Hypertension·Nour-Mounira Z BakkarSouha A Fares
Jun 1, 2021·Journal of Hypertension·Hao-Chih ChangHao-Min Cheng
Oct 9, 2021·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Toshinori Yuasa, Mitsuru Ohishi

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