High-speed alignment optimization of digital optical phase conjugation systems based on autocovariance analysis in conjunction with orthonormal rectangular polynomials

Journal of Biomedical Optics
Ashton S HemphillLihong V Wang

Abstract

Digital optical phase conjugation (DOPC) enables many optical applications by permitting focusing of light through scattering media. However, DOPC systems require precise alignment of all optical components, particularly of the spatial light modulator (SLM) and camera, in order to accurately record the wavefront and perform playback through the use of time-reversal symmetry. We present a digital compensation technique to optimize the alignment of the SLM in five degrees of freedom, permitting focusing through thick scattering media with a thickness of 5 mm and transport scattering coefficient of 2.5  mm  -  1 while simultaneously improving focal quality, as quantified by the peak-to-background ratio, by several orders of magnitude over an unoptimized alignment.

References

Dec 23, 2003·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Aner Lev, Bruno Sfez
Aug 19, 2007·Optics Letters·I M Vellekoop, A P Mosk
Sep 4, 2007·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Virendra N Mahajan, Guang-ming Dai
Jan 1, 2008·Nature Photonics·Zahid YaqoobChanghuei Yang
Aug 3, 2010·Nature Methods·Vasilis Ntziachristos
Jun 6, 2013·Applied Optics·Jiamiao YangZhigang Li
Feb 25, 2014·Optics Letters·Jiamiao YangHongwei Jiang
Jun 13, 2014·Applied Optics·Jiamiao YangXu Wang
Jan 27, 2015·Optica·Edward Haojiang ZhouBenjamin Judkewitz
May 15, 2015·Optics Express·Ivo M Vellekoop
Jun 16, 2015·Optics Express·Moonseok KimWonshik Choi
Jan 1, 2015·Nature Photonics·Roarke HorstmeyerChanghuei Yang
Sep 15, 2016·Journal of Biomedical Optics·Ashton S HemphillLihong V Wang

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