High speed intravascular photoacoustic imaging with fast optical parametric oscillator laser at 1.7 μm

Applied Physics Letters
Zhonglie PiaoZhongping Chen

Abstract

Intravascular photoacoustic imaging at 1.7 μm spectral band has shown promising capabilities for lipid-rich vulnerable atherosclerotic plaque detection. In this work, we report a high speed catheter-based integrated intravascular photoacoustic/intravascular ultrasound (IVPA/IVUS) imaging system with a 500 Hz optical parametric oscillator laser at 1725 nm. A lipid-mimicking phantom and atherosclerotic rabbit abdominal aorta were imaged at 1 frame per second, which is two orders of magnitude faster than previously reported in IVPA imaging with the same wavelength. Clear photoacoustic signals by the absorption of lipid rich deposition demonstrated the ability of the system for high speed vulnerable atherosclerotic plaques detection.

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Citations

Apr 26, 2016·Applied Physics Letters·Zhonglie PiaoChang-Seok Kim
Jan 17, 2017·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Donald VanderLaanStanislav Emelianov
Jul 12, 2017·Journal of Biomedical Optics·Changhoon ChoiChulhong Kim
Jul 14, 2016·Journal of Biomedical Optics·Pratik SamantLiangzhong Xiang
Sep 17, 2020·Journal of Biophotonics·Heng GuoLei Xi
Apr 14, 2018·Optics Letters·Kedi XiongDa Xing
Dec 12, 2018·Biomedical Engineering Letters·Yan Li, Zhongping Chen
Dec 20, 2019·Tissue Engineering. Part B, Reviews·Binita ShresthaEric M Brey
Apr 21, 2020·Journal of Innovative Optical Health Sciences·Yan LiZhongping Chen
Nov 19, 2020·Journal of Biophotonics·Mingsheng LiLidai Wang
Jan 15, 2017·Computers in Biology and Medicine·Sun ZhengHan Duoduo

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