High Stroke Volume Variation Method by Mannitol Administration Can Decrease Blood Loss During Donor Hepatectomy

Medicine
Hyungseok SeoYoung-Kug Kim

Abstract

Optimal fluid management to reduce blood loss during donor hepatectomy is important for maximizing donor safety. Mannitol can induce osmotic diuresis, helping prevent increased intravascular volume status. We therefore evaluated the effect of high stroke volume variation (SVV) method by mannitol administration and fluid restriction on blood loss during donor hepatectomy.In this prospective study, 64 donors scheduled for donor right hepatectomy were included and allocated into 2 groups. In group A, the SVV value of each patient was maintained at 10% to 20% during hepatic resection with 0.5 g/kg mannitol administration and fluid restriction at a rate of 2 to 4 mL/kg/h. In group B, the SVV value was maintained at <10% by fluid administration at a rate of 6 to 10 mL/kg/h without diuretic administration during surgery. Intraoperative blood loss was estimated by the loss of red cell mass. Surgeon satisfaction scores and postoperative outcomes, including acute kidney injury, abnormal chest radiographic findings, and hospital stay duration, were also assessed.SVV during hepatectomy was significantly higher in group A than in group B (11.0 ± 1.7 vs 6.5 ± 1.1, P < 0.001). The red cell mass loss was significantly lower in group A than in ...Continue Reading

References

Nov 14, 1997·Transfusion·M E BrecherL T Goodnough
Mar 21, 2003·The New England Journal of Medicine·David C McGee, Michael K Gould
May 25, 2006·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Salleh IbrahimYu-Fan Cheng
Jul 25, 2006·BMJ : British Medical Journal·Kwok M Ho, David J Sheridan
Dec 19, 2006·Journal of Clinical Anesthesia·Georgia KostopanagiotouVassilios Smyrniotis
Jan 30, 2007·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Claus U NiemannJohn P Roberts
Apr 11, 2008·Critical Care Medicine·Sean M BagshawJohn A Kellum
Jun 19, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Sumit R MajumdarKoon K Teo
Jul 25, 2009·The Journal of Surgical Research·Wisam KhouryAvi A Weinbroum
Jan 21, 2010·Anaesthesia·K M Ho, B M Power
May 29, 2010·Archives of Gynecology and Obstetrics·Hanan M F Al KadriHani M Tamim
Aug 21, 2012·Critical Care : the Official Journal of the Critical Care Forum·Gudrun BragadottirSven-Erik Ricksten
Jun 19, 2013·Transplantation Proceedings·D-B MoonC-S Park
Oct 24, 2013·Annals of Surgical Oncology·Erik M Dunki-JacobsRobert C G Martin
Mar 18, 2015·World Journal of Gastroenterology : WJG·Kyong Joo LeeHyun Il Seo
Aug 21, 2015·World Journal of Gastroenterology : WJG·Ahrong KimHong-Jae Jo
Dec 17, 2015·World Journal of Gastroenterology : WJG·Seong-Soo ChoiYoung-Kug Kim

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Citations

Sep 19, 2018·Minerva anestesiologica·Mario DauriStefano Di Girolamo
Jul 31, 2019·Annals of Medicine and Surgery·Laurence WeinbergChris Christophi
Jun 5, 2021·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Yasmin Abdelsalam KamelKhaled Ahmed Yassen

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