High-throughput degradome sequencing can be used to gain insights into microRNA precursor metabolism

Journal of Experimental Botany
Yijun MengMing Chen

Abstract

The approximately 21 nucleotide microRNAs (miRNAs) are one type of well-defined small RNA species, and they play critical roles in various biological processes in organisms. In plants, most miRNAs exert repressive regulation on their targets through cleavage, and a number of miRNA-target pairs have been validated either by modified 5' RACE (rapid amplification of cDNA ends), or by newly developed high-throughput strategies. All these data have greatly advanced our understanding of the regulatory roles of plant miRNAs. On the other hand, deep insights into miRNA precursor processing, and miRNA- or miRNA*-mediated self-regulation of their host precursors could be gained from high-throughput degradome sequencing data, based on the general framework of miRNA generation in plants. Here, the focus is on the recent research progress on this issue, and several interesting points were raised.

References

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Citations

Jan 26, 2011·Briefings in Bioinformatics·Yijun MengMing Chen
Jul 20, 2012·Briefings in Bioinformatics·Chaogang ShaoYijun Meng
Aug 20, 2010·Nucleic Acids Research·Yijun MengMing Chen
Jun 10, 2011·Nucleic Acids Research·Paulina JackowiakMarek Figlerowicz
Oct 18, 2011·Plant Physiology·Yijun MengMing Chen
Feb 5, 2016·BMC Plant Biology·Edna Gicela Ortiz MoreaFabio Tebaldi Siveira Nogueira
Dec 31, 2015·The Plant Journal : for Cell and Molecular Biology·Tengfei LiuZhixi Tian
Aug 4, 2015·Journal of Genetics and Genomics = Yi Chuan Xue Bao·Caijuan TianJin-Long Qiu
Mar 24, 2012·Journal of Experimental Botany·Ehsan TavakkoliGlenn K McDonald
Jan 10, 2018·Frontiers in Plant Science·Wei-Wei LiuYu-Shi Luan
Nov 30, 2018·Frontiers in Genetics·Dongliang YuYijun Meng

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