High-throughput determination of quantitative structure-property relationships using a resonant multisensor system: solvent resistance of bisphenol a polycarbonate copolymers

Analytical Chemistry
Radislav A PotyrailoWilliam G Morris

Abstract

Polymers are important materials for sensor, microfluidic, and other demanding applications. High-throughput screening methodology has been applied for the evaluation of the solvent resistance of a family of polycarbonate copolymers prepared from the reaction of bisphenol A (BPA), hydroquinone (HQ), and resorcinol (RS) in different solvents of practical importance, such as chloroform, tetrahydrofuran (THF), and methyl ethyl ketone (MEK). We employed a 24-channel acoustic-wave sensor system that provided previously unavailable capabilities for parallel evaluation of polymer solvent resistance. This high-throughput polymer evaluation approach assisted in construction of detailed solvent-resistance maps of polycarbonate copolymers and in determination of quantitative structure-property relationships. The best absolute solvent resistance of all studied copolymers was achieved in MEK, followed by chloroform and THF. A D-optimal mixture design was employed to explore the relationship between the copolymer compositions and their solvent resistance. The applied special cubic model for each solvent took into account the primary mixture terms such as BPA, HQ, and RS; binary interaction terms such as BPA-HQ, BPA-RS, and HQ-RS; and a terna...Continue Reading

References

Oct 2, 2003·Journal of the American Chemical Society·Michele SumanEnrico Dalcanale
Feb 3, 2004·Nature Materials·Eric J Amis
Jul 2, 2004·Nature Materials·Hideomi Koinuma, Ichiro Takeuchi
Nov 9, 2004·Journal of Combinatorial Chemistry·Radislav A PotyrailoPatrick J McCloskey
Apr 6, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Zuzanna T CyganEric J Amis
Oct 31, 2008·Talanta·Holger Becker, Laurie E Locascio

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Citations

Jun 8, 2011·ACS Combinatorial Science·Radislav PotyrailoHubert Lam
Aug 4, 2007·The Review of Scientific Instruments·Radislav A Potyrailo, William G Morris
Jul 21, 2007·Angewandte Chemie·Wilhelm F MaierSimone Sieg
Jan 24, 2008·Chemical Reviews·Radislav A Potyrailo, Vladimir M Mirsky

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