High-throughput evaluation of organic contaminant removal efficiency in a wastewater treatment plant using direct injection UHPLC-Orbitrap-MS/MS

Environmental Science. Processes & Impacts
Zhe LiMichael S McLachlan

Abstract

The removal efficiency (RE) of organic contaminants in wastewater treatment plants (WWTPs) is a major determinant of the environmental impact of these contaminants. However, RE data are available for only a few chemicals due to the time and cost required for conventional target analysis. In the present study, we applied non-target screening analysis to evaluate the RE of polar contaminants, by analyzing influent and effluent samples from a Swedish WWTP with direct injection UHPLC-Orbitrap-MS/MS. Matrix effects were evaluated by spiking the samples with isotope-labeled standards of 40 polar contaminants. For 85% of the compounds, the matrix effects in the influent and effluent were not significantly different. Approximately 10 000 compounds were detected in the wastewater, of which 319 were identified by using the online database mzCloud. Level 1 identification confidence was achieved for 31 compounds for which we had reference standards, and level 2 was achieved for the remainder. RE was calculated from the ratio of the peak areas in the influent and the effluent from the non-target analysis. Good agreement was found with RE determined from the target analysis of the target compounds. The method generated reliable estimates of ...Continue Reading

References

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Citations

May 18, 2021·Archives of Environmental Contamination and Toxicology·Gabrielle Rabelo QuadraAnna Sobek
Jan 25, 2019·Environmental Science & Technology·Zhe Li, Michael S McLachlan
Oct 27, 2020·Environmental Science & Technology·Claudia CollAnna Sobek

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Methods Mentioned

BETA
PCA

Software Mentioned

PaDEL Descriptors
Compound Discoverer
mzCloud
Xcalibur
Software for Chemometric Analysis ( SCAN )

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