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High-throughput functional annotation of influenza A virus genome at single-nucleotide resolution

bioRxiv

May 31, 2014

Nicholas C. WuRen X. Sun

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Abstract

A novel genome-wide genetics platform is presented in this study, which permits functional interrogation of all point mutations across a viral genome in parallel. Here we generated the first fitness profile of individual point mutations across the influenza virus genome. Critical residu...read more

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  • High-throughput functional annotation of influenza A virus genome at single-nucleotide resolution

    bioRxiv

    May 31, 2014

    Nicholas C. WuRen X. Sun

    PMID: 990005702

    DOI: 10.1101/005702

    Abstract

    A novel genome-wide genetics platform is presented in this study, which permits functional interrogation of all point mutations across a viral genome in parallel. Here we generated the first fitness profile of individual point mutations across the influenza virus genome. Critical residu...read more

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    10
    Paper Details
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