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High-throughput functional annotation of influenza A virus genome at single-nucleotide resolution

bioRxiv

May 31, 2014

Nicholas C WuRen Sun

Abstract

A novel genome-wide genetics platform is presented in this study, which permits functional interrogation of all point mutations across a viral genome in parallel. Here we generated the first fitness profile of individual point mutations across the influenza virus genome. Critical residu...read more

Mentioned in this Paper

Genome-Wide Association Study
Study
Viral Genome Location
Virus
Genome
Vaccines
Genetic Manipulation
Pharmacologic Substance
Influenza A virus
Nucleotides
5
10
Paper Details
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High-throughput functional annotation of influenza A virus genome at single-nucleotide resolution

bioRxiv

May 31, 2014

Nicholas C WuRen Sun

PMID: 990005702

DOI: 10.1101/005702

Abstract

A novel genome-wide genetics platform is presented in this study, which permits functional interrogation of all point mutations across a viral genome in parallel. Here we generated the first fitness profile of individual point mutations across the influenza virus genome. Critical residu...read more

Mentioned in this Paper

Genome-Wide Association Study
Study
Viral Genome Location
Virus
Genome
Vaccines
Genetic Manipulation
Pharmacologic Substance
Influenza A virus
Nucleotides
5
10
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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