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High-throughput screening using siRNA (RNAi) libraries

Expert Review of Molecular Diagnostics

May 11, 2007

Meihong ChenZicai Liang

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Abstract

RNA interference (RNAi) has become one of the most important research tools in functional genomics analysis ever since the discovery of the phenomenon. The robustness of the method has enabled construction of RNAi libraries in the forms of long double-stranded RNA or short-interfering R...read more

Mentioned in this Paper

Shuttle Vectors
Genome
RNA, Small Interfering
RNA, Double-Stranded
Genetic Screening Method
Genomics
cDNA Library
RNA Interference
Short Hairpin RNA
Functional Genomics
Paper Details
References
  • References81
  • Citations5
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High-throughput screening using siRNA (RNAi) libraries

Expert Review of Molecular Diagnostics

May 11, 2007

Meihong ChenZicai Liang

PMID: 17489735

DOI: 10.1586/14737159.7.3.281

Abstract

RNA interference (RNAi) has become one of the most important research tools in functional genomics analysis ever since the discovery of the phenomenon. The robustness of the method has enabled construction of RNAi libraries in the forms of long double-stranded RNA or short-interfering R...read more

Mentioned in this Paper

Shuttle Vectors
Genome
RNA, Small Interfering
RNA, Double-Stranded
Genetic Screening Method
Genomics
cDNA Library
RNA Interference
Short Hairpin RNA
Functional Genomics

Feeds With Similar Papers

RNAi & Gene Silencing

RNA Interference (RNAi) pathway is involved in post-transcriptional gene silencing, transcriptional silencing and epigenetic silencing as well as its use as a tool for forward genetics and therapeutics. Discover the latest research here.

Related Papers

Nature

RNA interference

NatureJuly 12, 2002
Gregory J Hannon
Briefings in Functional Genomics & Proteomics

Genome-wide RNAi as a route to gene function in Drosophila

Briefings in Functional Genomics & ProteomicsSeptember 10, 2004
David Kuttenkeuler, Michael Boutros
Paper Details
References
  • References81
  • Citations5
12345...

Download from

Publisher
PubMed
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