High urinary excretion of glycosaminoglycans: a possible marker of glomerular involvement in diabetes

Metabolism: Clinical and Experimental
Giovanni GambaroB Baggio

Abstract

Many insulin-dependent diabetic patients with albuminuria in the "not at risk range" for diabetic nephropathy present high urinary excretion rates of glycosaminoglycans. A lysine provocative test in these subjects disclosed abnormal urinary excretion of albumin, unlike findings obtained in insulin-dependent diabetic patients with normal urinary excretion rates of glycosaminoglycans. These data support the hypothesis that high urinary excretion of glycosaminoglycans is a marker of glomerular involvement in diabetes mellitus.

Citations

Oct 1, 1994·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·P Ljungberg
Oct 12, 2004·BMC Ophthalmology·Yasemin BudakDilek Yavuz
Feb 15, 2008·Diabetes/metabolism Research and Reviews·Anna Popławska-KitaMaria Górska
Aug 15, 1990·Clinica Chimica Acta; International Journal of Clinical Chemistry·A S Reddi

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