Higher body mass index is associated with lower foot health in patients with rheumatoid arthritis: baseline results of the Amsterdam-Foot cohort

Scandinavian Journal of Rheumatology
Rutger DahmenMarike van der Leeden

Abstract

Objective: Obesity is highly prevalent in patients with rheumatoid arthritis (RA), with likely impact on weight-bearing foot joints. We explored the associations between body mass index (BMI) and measures of foot health in patients with RA and foot complaints.Method: We examined patients with RA presenting for their first custom-made therapeutic footwear or foot orthoses. Domains of foot health comprised: foot pain, foot-related activity limitations, forefoot plantar pressure, foot synovitis, and foot deformity. In regression analyses, BMI was the independent variable and foot health domains were the dependent variables.Results: The cohort at baseline comprised 230 patients [mean ± sd age 58 ± 13 years, 80% female, mean ± sd disease duration 10 ± 9 years, and median (interquartile range) BMI 26.7 (23.5-30.1) kg/m2]. Small to modest statistically significant associations were found in the majority of the measures studied between a higher BMI and more foot pain, more foot-related activity limitations, higher in-shoe measured forefoot plantar pressure, and the presence of foot synovitis. No relationships were found between BMI and barefoot measured forefoot plantar pressure or foot deformity.Conclusion: BMI is negatively associate...Continue Reading

References

Nov 1, 1994·Foot & Ankle International·J MichelsonD Hellmann
Dec 26, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·A P HillsO Bar-Or
Feb 11, 2004·Foot & Ankle International·Amy M WickmanDainius Juknelis
Jun 4, 2005·Arthritis and Rheumatism·Philip HelliwellJames Woodburn
Jul 8, 2005·Journal of Clinical Nursing·Amelia Williamson, Barbara Hoggart
Aug 15, 2006·Annals of the Rheumatic Diseases·G A MatricaliR Westhovens
Mar 7, 2007·Clinical Rheumatology·Augusto García-PomaCecilia P Chung
Apr 3, 2008·Arthritis and Rheumatism·Esperanza NaredoUNKNOWN Ultrasound Group of The Spanish Society of Rheumatology
Dec 10, 2009·Clinical Rheumatology·Simon J OtterKaren Walker-Bone
May 15, 2010·Journal of Foot and Ankle Research·Karl B LandorfSusie Hudson
Sep 28, 2010·Lancet·David L ScottTom W J Huizinga
Feb 12, 2011·Journal of Foot and Ankle Research·Marike van der LeedenJoost Dekker
Jan 10, 2012·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Scott C WearingJames E Smeathers
Apr 20, 2012·Arthritis Care & Research·Frederick Wolfe, Kaleb Michaud
Feb 2, 2013·Journal of Foot and Ankle Research·Elly Budiman-MakRodney M Stuck
Aug 6, 2014·Annals of the Rheumatic Diseases·Joshua F BakerPhilip G Conaghan
Aug 12, 2015·Gait & Posture·Karen J Mickle, Julie R Steele
Dec 4, 2015·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Veronica CimolinAlessandro Sartorio
Jul 21, 2016·Clinical Biomechanics·Carina Price, Christopher Nester
Apr 24, 2018·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Veena K RanganathDavid A Elashoff

❮ Previous
Next ❯

Citations

Oct 15, 2021·Journal of Empirical Research on Human Research Ethics : JERHRE·Minna StoltHelena Leino-Kilpi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.