Higher Impulsivity As a Distinctive Trait of Severe Cocaine Addiction among Individuals Treated for Cocaine or Alcohol Use Disorders

Frontiers in Psychiatry
Nuria García-MarchenaFernando Rodríguez de Fonseca

Abstract

Despite alcohol being the most often used addictive substance among addicted patients, use of other substances such as cocaine has increased over recent years, and the combination of both drugs aggravates health impairment and complicates clinical assessment. The aim of this study is to identify and characterize heterogeneous subgroups of cocaine- and alcohol-addicted patients with common characteristics based on substance use disorders, psychiatric comorbidity and impulsivity. A total of 214 subjects with cocaine and/or alcohol use disorders were recruited from outpatient treatment programs and clinically assessed. A latent class analysis was used to establish phenotypic categories according to diagnosis of cocaine and alcohol use disorders, mental disorders, and impulsivity scores. Relevant variables were examined in the latent classes (LCs) using correlation and analyses of variance and covariance. Four LCs of addicted patients were identified:Class 1(45.3%) formed by alcohol-dependent patients exhibiting lifetime mood disorder diagnosis and mild impulsivity;Class 2(14%) formed mainly by lifetime cocaine use disorder patients with low probability of comorbid mental disorders and mild impulsivity;Class 3(10.7%) formed by coca...Continue Reading

References

Jan 1, 1994·Journal of Addictive Diseases·S T HigginsG J Badger
Aug 1, 1996·Therapeutic Drug Monitoring·P JatlowR H Roth
Sep 1, 1996·Alcoholism, Clinical and Experimental Research·C S MartinR E Tarter
Aug 28, 2003·Experimental and Clinical Psychopharmacology·Stephen P Whiteside, Donald R Lynam
Oct 1, 1955·Journal of Consulting Psychology·R M REITAN
Jul 1, 2004·Neuroscience and Biobehavioral Reviews·Sharon Dawe, Natalie J Loxton
Apr 11, 2006·Substance Use & Misuse·Barris P MalcolmBernard Segal
Feb 3, 2007·The British Journal of Psychiatry : the Journal of Mental Science·Carol L M CatonBella Schanzer
Jan 18, 2008·Addiction·M Jesús HerreroUNKNOWN ITINERE Investigators
Oct 23, 2008·The American Journal of Cardiology·Deborah B DiercksUNKNOWN ADHERE Scientific Advisory Committee and Investigators
Dec 18, 2008·Personality and Individual Differences·Melissa A Cyders, Gregory T Smith
Jul 10, 2009·Psychology of Addictive Behaviors : Journal of the Society of Psychologists in Addictive Behaviors·Tamika C B ZapolskiGregory T Smith
Aug 6, 2009·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Muhammad U FarooqMehul Patel
Aug 28, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·George F Koob, Nora D Volkow
Feb 13, 2010·Addiction Biology·Danielle M DickKenneth Sher
Apr 21, 2010·Addiction·James D SargentReiner Hanewinkel
Aug 31, 2010·Drug and Alcohol Dependence·Marta TorrensUNKNOWN psyCoBarcelona Group
Sep 11, 2010·Drug and Alcohol Dependence·Louisa DegenhardtWayne D Hall
Mar 7, 2012·Drug and Alcohol Dependence·Laura Moreno-LópezAntonio Verdejo-García
Aug 23, 2012·Psychiatry Research·Esperanza Vergara-MoraguesAntonio Verdejo García
Oct 3, 2012·Drug and Alcohol Dependence·Cleo L CrunelleWim van den Brink
Jun 27, 2013·Addiction Biology·Katrin H PrellerBoris B Quednow
Jul 24, 2013·Journal of Gastroenterology and Hepatology·Eric S OrmanRamon Bataller
Mar 25, 2014·Annals of the New York Academy of Sciences·J David JentschZachary T Pennington
Apr 29, 2014·Current Behavioral Neuroscience Reports·Marci R Mitchell, Marc N Potenza
Dec 17, 2014·Journal of Addiction·Sheree M SchragerStephen E Lankenau
Aug 16, 2015·Cell·Nora D Volkow, Marisela Morales
Apr 8, 2017·Journal of Parkinson's Disease·Laura BrennanDaniel Weintraub

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Citations

Feb 27, 2020·Behavioural Pharmacology·William S HyattWilliam E Fantegrossi
Apr 20, 2020·Psychiatry and Clinical Neurosciences·Taiane de Azevedo CardosoFlavio Kapczinski
Sep 7, 2019·Nutrients·Rachel C AdamsNatalia S Lawrence
Aug 4, 2020·Epilepsy & Behavior : E&B·Marte SyvertsenAnna Smith

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