Higher IQ in juvenile myoclonic epilepsy: Dodging cognitive obstacles and "masking" impairments

Epilepsy & Behavior : E&B
Patrícia RzezakKette Valente

Abstract

Executive deficits and impulsiveness are extensively reported in juvenile myoclonic epilepsy (JME). Previous literature suggests that intelligence may mediate these deficits. In this study, we evaluated and compared the performance of adults with JME with high and low intelligence quotient (IQ) and controls on tasks for executive function (EF) and impulsive traits. We investigated the neuropsychological performance of 53 adults with JME and below average IQ (57% women; 26.9 [±7.88] years; mean IQ: 89.8 [±5.1]), 26 adults with JME and average or above average IQ (53.8% women; 28.2 [±9.33] years; mean IQ: 110.7 [±8.3]), 38 controls with below average IQ (55% women; 28.4 [±8.4] years; mean IQ: 90.1 [±5.8]), and 31 controls with average or above average IQ (61.3% women; 32.20 [±11.3] years; mean IQ: 111.6 [±10.5]) with a comprehensive battery of neuropsychological tests that measure executive/attentional function. Impulsive traits were assessed using the Cloninger et al.'s Temperament and Character Inventory (novelty seeking (NS) domain). The group with JME with higher IQ presented worse performance compared with controls with higher IQ on Controlled Oral Word Association (COWA) and Wisconsin Card Sorting Test (WCST) (errors). This...Continue Reading

Citations

May 17, 2019·Applied Neuropsychology. Child·Lydia van den BergJaap van der Meere
Mar 27, 2020·Frontiers in Neurology·Corey RatcliffeLorenzo Caciagli
Jul 19, 2021·Epilepsy & Behavior : E&B·Taylor M McMillanBruce Hermann
Aug 21, 2021·Epilepsy & Behavior : E&B·Sofie MangaardChristoph P Beier
Sep 24, 2021·Nature Reviews. Neurology·Bruce P HermannCarrie R McDonald
Oct 18, 2020·Seizure : the Journal of the British Epilepsy Association·André Peres GamaLaura Maria Guilhoto

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