Abstract
Vaginolysin (VLY), a cytotoxic protein produced by Gardnerella vaginalis, may contribute to bacterial vaginosis. We observed that women with G. vaginalis, low levels of lactobacilli, history of vaginal douching, higher Nugent scores, and higher vaginal pH had increased VLY. Inflammatory markers were not highly expressed with increasing VLY. Vaginolysin's role in bacterial vaginosis warrants further evaluation.
References
Feb 1, 1991·Journal of Clinical Microbiology·R P NugentS L Hillier
Nov 1, 1993·American Journal of Obstetrics and Gynecology·J J Platz-ChristensenN Wiqvist
Jul 29, 2000·The Journal of Infectious Diseases·K Sturm-RamirezP J Kanki
Aug 31, 2001·Human Reproduction·E R BoskeyT R Moench
May 23, 2002·The Journal of Infectious Diseases·Sabina CauciFranco Quadrifoglio
Nov 13, 2004·Current Infectious Disease Reports·Sabina Cauci
May 5, 2005·The Journal of Infectious Diseases·M Reza ZariffardGregory T Spear
Jan 21, 2006·The Journal of Infectious Diseases·Spencer R HedgesJane R Schwebke
Aug 24, 2007·American Journal of Obstetrics and Gynecology·Sabina CauciKelly McCollum
Apr 9, 2008·Journal of Bacteriology·Shari E GelberAdam J Ratner
Apr 17, 2009·PloS One·Tara M RandisAdam J Ratner
Jun 6, 2009·BMC Microbiology·Hans VerstraelenMario Vaneechoutte
Apr 27, 2010·PloS One·Sujatha SrinivasanDavid N Fredricks
Nov 10, 2010·Proceedings of the National Academy of Sciences of the United States of America·Jean M MacklaimGregor Reid
Dec 7, 2011·The American Journal of the Medical Sciences·David H Martin
Apr 19, 2012·BMC Microbiology·Cindy M LiuLance B Price
Dec 4, 2012·Reproductive Sciences·Amy McMillanGregor Reid
Aug 13, 2013·International Journal of Medical Sciences·Joana CastroNuno Cerca
Oct 2, 2013·Infection and Immunity·Tara M RandisAdam J Ratner
Nov 14, 2013·PloS One·Deirdre E O'HanlonRichard A Cone
Aug 30, 2014·BMC Infectious Diseases·Rebecca M BrotmanJessica M Rath
Jun 27, 2015·Scientific Reports·Joana CastroNuno Cerca
Jun 27, 2017·NPJ Biofilms and Microbiomes·Joana CastroNuno Cerca
Citations
Jan 30, 2019·Infection and Immunity·Erin M GarciaKimberly K Jefferson
Jul 14, 2020·Frontiers in Cellular and Infection Microbiology·Qian YangWeiguo Lu
Jan 31, 2020·Frontiers in Cellular and Infection Microbiology·Milda Pleckaityte
Nov 9, 2020·Microbial Cell Factories·Wallace Jeng Yang CheeLeslie Thian Lung Than
Jan 28, 2021·Pathogens·Erin M GarciaKimberly K Jefferson