Higher prevalence of vitamin D deficiency in German pregnant women compared to non-pregnant women

Archives of Gynecology and Obstetrics
Sandra GellertAndreas Hahn

Abstract

Adequate vitamin D status is crucial for normal development of the fetus and for maternal health. As data on vitamin D status (25-hydroxyvitamin D, 25(OH)D) in German women of different states of pregnancy were not available, this study compared the vitamin D status of German women in all trimesters of pregnancy with that of non-pregnant women. The study sample of 858 women (18-45 years) was recruited from April 2013 to March 2015 as a part of the cross-sectional Germany-wide VitaMinFemin study. Serum 25(OH)D levels were determined using chemiluminescence immunoassay. A total of 78.1% of the pregnant women and 53.9% of the non-pregnant women had a vitamin D status <50.0 nmol/L (p < 0.001). In pregnant women, the multivariate binary analysis showed that winter [odds ratio (OR) 13.5], longitude of residence between 6.3°E and 8.9°E (OR 2.0) or 9.0°E and 10.9°E (OR 2.3) and third trimester (OR 2.3) were associated with a higher risk of vitamin D status <25.0 nmol/L, whereas increasing age per one year (OR 0.9) with a lower risk. Compared with non-pregnant women, pregnant women were 3.7 times more likely to have a vitamin D status <25.0 nmol/L. A low vitamin D status is prevalent among German pregnant women and should be improved to...Continue Reading

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Citations

Sep 29, 2017·International Journal of Environmental Research and Public Health·Regina WierzejskaMagdalena Siuba-Strzelińska
Aug 21, 2020·Maternal & Child Nutrition·Shahida RabbaniZia Ul-Haq
Aug 2, 2018·Frontiers in Endocrinology·Stefan PilzArmin Zittermann
Feb 24, 2018·Frontiers in Endocrinology·Regina WierzejskaMagdalena Siuba-Strzelińska
May 9, 2019·The Journal of Medical Investigation : JMI·Eishi SogawaMinoru Irahara
Oct 17, 2018·International Journal of Environmental Research and Public Health·Stefan PilzWinfried März
Feb 6, 2020·Deutsches Ärzteblatt International·Alexandra JungertSabine Rohrmann
Sep 19, 2018·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Marie CourbebaisseAlexandra Benachi
Aug 11, 2021·The Journal of Obstetrics and Gynaecology Research·Ichiro YamadeHiroshi Hatayama
Sep 3, 2021·Australian and New Zealand Journal of Public Health·Kate M MillerAveni Haynes

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