Higher retention and viral suppression with adolescent-focused HIV clinic in South Africa

PloS One
Brian C ZanoniJessica E Haberer

Abstract

To determine retention in care and virologic suppression among HIV-infected adolescents and young adults attending an adolescent-friendly clinic compared to those attending the standard pediatric clinic at the same site. Retrospective cohort analysis. Government supported, hospital-based antiretroviral clinic in KwaZulu-Natal, South Africa. Two hundred forty-one perinatally HIV-infected adolescents and young adults aged 13 to 24 years attending an adolescent-friendly clinic or the standard pediatric clinic from April 2007 to November 2015. Attendance in an adolescent-friendly clinic compared to a standard pediatric clinic. Retention in care defined as one clinic visit or pharmacy refill in the prior 6 months; HIV-1 viral suppression defined as < 400 copies/ml. Overall, among 241 adolescents and young adults, retention was 89% (214/241) and viral suppression was 81% (196/241). Retention was higher among those attending adolescent clinic (95%) versus standard pediatric clinic (85%; OR 3.7; 95% confidence interval (CI) 1.2-11.1; p = 0.018). Multivariable logistic regression adjusted for age at ART initiation, gender, pre-ART CD4 count, months on ART, and tuberculosis history indicated higher odds of retention in adolescents and yo...Continue Reading

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Jul 10, 2018·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Edith ApondiSamuel Ayaya
Aug 8, 2018·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Nora E RosenbergAudrey E Pettifor
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Nov 26, 2021·Journal of the International Association of Providers of AIDS Care·Zaida Orth, Brian van Wyk
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