Higher serum triglyceride level in patients with acute ischemic stroke is associated with lower infarct volume on CT brain scans

European Neurology
Slaven PikijaNedeljko Sokol

Abstract

We investigated the relationship between serum triglyceride level and acute ischemic stroke severity using infarct volume on CT brain scans as a marker. A total of 121 consecutive acute ischemic stroke patients (53 males and 68 females, age 47-93 years) with anterior circulation (75%), posterior circulation (9%) or lacunar infarcts (16%) were examined. All patients were admitted within 24 h of the symptom onset, and CT scans were taken over the subsequent 24-72 h. With adjustment for the infarct type, age, sex, timing of CT imaging (24-36, >36-48 or >48-72 h since admission), atrial fibrillation, hypertension, fasting cholesterol and glucose levels, a higher (> or =1.70 mmol/l) fasting serum triglyceride level (within 24 h after admission) was associated with a lower infarct volume (p = 0.014). In line with a recent report on milder clinical symptoms in acute ischemic stroke patients with higher triglycerides, the results suggest an independent association between serum triglyceride level and stroke severity.

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Citations

Jul 2, 2008·Clinical Chemistry and Laboratory Medicine : CCLM·Ana-Maria SimundicVida Demarin
Dec 15, 2010·Neurology India·Chih-Ying WuHsu-Huei Weng
May 15, 2012·Journal of the Neurological Sciences·Kang-Ho ChoiKi-Hyun Cho
May 24, 2012·Acta Neurologica Scandinavica·J PutaalaT Tatlisumak
May 26, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Dong-Won ShinJi-Sung Lee
Apr 17, 2012·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Slaven PikijaDunja Dukši
Jan 9, 2013·European Neurology·Mi-Yeon EunSeong-Beom Koh
Oct 25, 2016·Metabolic Brain Disease·Konstantinos TziomalosApostolos I Hatzitolios
Jan 1, 2013·Neuroscience Journal·Minal JainLatha Ganti Stead
Jul 22, 2019·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ivana CelapAna-Maria Simundic

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