Higher systolic blood pressure is associated with progression of carotid intima-media thickness in patients with chronic kidney disease

Kidney International
Jessica KendrickDirk Sander

Abstract

To examine the relationship between systolic blood pressure and progression of carotid intima-media thickness in patients with chronic kidney disease (CKD), we studied 3364 patients from a community-based cohort of elderly individuals of whom 724 had CKD defined as creatinine clearances of stage 3 or less. The contribution of systolic blood pressure was evaluated in four ranges (<120, 120-129, 130-139, and > or = 140 mm Hg). All multiple linear regression analyses were adjusted for traditional and nontraditional cardiovascular risk factors. The higher ranges of systolic blood pressure at baseline were associated with a greater carotid intima-media thickness at the initiation of the study in patients with or without CKD. Covariate-adjusted averages of carotid intima-media thickness at the initiation of the study in patients with CKD significantly increased across the four strata of systolic blood pressure. Higher systolic blood pressure at baseline was associated with a significantly greater yearly change in covariate-adjusted mean carotid intima-media thickness and vascular events in patients with CKD over a 4-year follow-up period.

References

Sep 1, 1991·European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies·B Vester, K Rasmussen
May 22, 1996·JAMA : the Journal of the American Medical Association·D LevyK K Ho
Aug 1, 1996·Kidney International·G M LondonF Metivier
Jul 21, 1998·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M Walser
Oct 25, 2001·Journal of the American Society of Nephrology : JASN·Francesco Antonio BenedettoCarmine Zoccali
Jan 17, 2002·The New England Journal of Medicine·R S VasanD Levy
Mar 26, 2002·JAMA : the Journal of the American Medical Association·Preston S KlassenWilliam F Owen
Jul 26, 2002·Journal of the American Society of Nephrology : JASN·Andrew G BostomEberhard Ritz
May 16, 2003·JAMA : the Journal of the American Medical Association·Aram V ChobanianUNKNOWN National High Blood Pressure Education Program Coordinating Committee
Jul 16, 2003·Annals of Internal Medicine·Andrew S LeveyUNKNOWN National Kidney Foundation
Aug 30, 2003·Stroke; a Journal of Cerebral Circulation·Irene M van der MeerJacqueline C M Witteman
Sep 6, 2003·Stroke; a Journal of Cerebral Circulation·M HollanderM M B Breteler
Apr 28, 2004·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Orhan KocamanTevfik Ecder
Jan 25, 2005·Lancet·A Meguid El Nahas, Aminu K Bello
Jun 3, 2005·Journal of the American Society of Nephrology : JASN·Tomas BerlUNKNOWN Collaborative Study Group
Aug 16, 2006·Atherosclerosis·Anna Kablak-ZiembickaKrzysztof Zmudka
Jan 16, 2007·Journal of Vascular Surgery·L NorgrenUNKNOWN TASC II Working Group
Feb 16, 2007·Journal of the American Society of Nephrology : JASN·Daniel E WeinerMark J Sarnak
Feb 21, 2007·Circulation·Judith HsiaUNKNOWN Women's Health Initiative Investigators
May 15, 2007·Journal of the American Society of Nephrology : JASN·Cheuk-Chun SzetoPhilip Kam-Tao Li
Nov 8, 2007·JAMA : the Journal of the American Medical Association·Josef CoreshAndrew S Levey
Mar 12, 2008·Nature Clinical Practice. Cardiovascular Medicine·Eric de GrootJohn Jp Kastelein
Apr 11, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Madhav V RaoGeorge Bakris
Mar 29, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Angela M DesbienDirk Sander
Apr 1, 2008·The American Journal of Medicine·Pantelis A SarafidisGeorge L Bakris
Apr 5, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Michel ChoncholDirk Sander
Oct 14, 2008·Atherosclerosis·Michael G ShlipakMark J Sarnak

❮ Previous
Next ❯

Citations

Jul 26, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Akira FunayamaIsao Kubota
Oct 8, 2013·Journal of Atherosclerosis and Thrombosis·Takashi IwakiriYujiro Asada
Apr 16, 2010·Kidney International·John P Middleton, Patrick H Pun
Aug 28, 2016·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Maria AbajoUNKNOWN Investigators of the NEFRONA study
Oct 6, 2011·Journal of Hypertension·Christos ChatzikyrkouMario Schiffer
Oct 30, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Keiji HiraiYoshiyuki Morishita

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.