Highly active antiretroviral therapy and cervical intraepithelial neoplasia

AIDS
Antonia L MooreMargaret A Johnson

Abstract

Highly active antiretroviral therapy (HAART) has improved HIV prognosis, but its effect on cervical intraepithelial neoplasia (CIN), which is associated with HIV, is uncertain. Among 71 HAART-treated women the prevalence of CIN before HAART was 55%. After a median of 10 months after starting HAART the prevalence had increased to 62% (P = 0.20); 13% of patients experienced regression of a CIN lesion, and this was most strongly associated with a greater increase in CD4 cell count. Such studies will provide the basis for guidelines for monitoring CIN in HIV-positive women in the HAART era.

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Citations

Mar 7, 2012·International Journal of Women's Health·Terrumun Z SwendeLaadi T Swende
Mar 22, 2005·Best Practice & Research. Clinical Obstetrics & Gynaecology·Z M Chirenje
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