Highly efficient construction of large molecular cavity using 1,3-alternate tetraoxacalix[2]arene[2]triazine as a platform

Chemical Communications : Chem Comm
Bao-Yong HouMei-Xiang Wang

Abstract

In the presence of K(2)CO(3) in refluxing THF, dichloro-substituted tetraoxacalix[2]arene[2]triazine, a readily available macrocyclic compound from cyanuric acid chloride and benzyl 1,3-dihydroxybenzoate, underwent highly efficient nucleophilic displacement reactions with bis-nucleophilic reagents of different geometry, length and chirality in a 2+2 fashion to produce large and size-tunable cavity bis-tetraoxacalix[2]arene[2]triazines in good to excellent yields.

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Citations

Sep 26, 2008·Chemical Communications : Chem Comm·Mei-Xiang Wang
Oct 28, 2009·The Journal of Organic Chemistry·En-Xuan ZhangMei-Xiang Wang
Jun 6, 2009·The Journal of Organic Chemistry·Bo YaoMei-Xiang Wang
Jan 2, 2010·The Journal of Organic Chemistry·Li-Xia WangMei-Xiang Wang

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