Highly Electrocatalytic, Durable, and Stretchable Nanohybrid Fiber for On-Body Sweat Glucose Detection

ACS Applied Materials & Interfaces
Phan Tan ToiNae-Eung Lee

Abstract

A conformal patch biosensor that can detect biomolecules is one promising technology for wearable sweat glucose self-monitoring. However, developing such a patch is challenging because conferring stretchability to its components is difficult. Herein, we demonstrate a platform for a nonenzymatic, electrochemical sensor patch: a wrinkled, stretchable, nanohybrid fiber (WSNF) in which Au nanowrinkles partially cover the reduced graphene oxide (rGO)/polyurethane composite fiber. The WSNF has high electrocatalytic activity because of synergetic effects between the Au nanowrinkles and the oxygen-containing functional groups on the rGO-supporting matrix which promote the dehydrogenation step in glucose oxidation. The WSNF offers stretchability, high sensitivity, low detection limit, high selectivity against interferents, and high ambient-condition stability, and it can detect glucose in neutral conditions. If this WSNF sensor patch were sewn onto a stretchable fabric and attached to the human body, it could continuously measure glucose levels in sweat to accurately reflect blood glucose levels.

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Citations

Feb 6, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Guanglei Li, Dan Wen
Aug 11, 2020·Analytical and Bioanalytical Chemistry·Raluca-Elena MunteanuSzilveszter Gáspár
Jun 28, 2019·Frontiers in Chemistry·Haizhou HuangLitao Sun
Sep 16, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Xiaoyang XuanShangqing Gong
Jan 23, 2021·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Tanveer A TabishRoger J Narayan
Feb 6, 2021·Sensors and Actuators. B, Chemical·Roozbeh GhaffariTyler R Ray
May 1, 2021·Advanced Healthcare Materials·Jinyuan ZhangChi Hwan Lee
Jun 22, 2021·Nanoscale·Linling XuAli Zavabeti
Jun 29, 2021·Advanced Materials Technologies·Le Minh Tu PhanSungbo Cho

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