Hippocampal influence on hyperreactivity induced by septal lesions.

Brain Research
F H Gage, D S Olton

Abstract

Rats were tested for their responses to 4 stimuli in order to measure hyperreactivity. Animals with septal lesions emitted the expected hyperreactivity. Lesions of the postcommisural fornix, precommissural fornix, or anterior hippocampus, administered 16 days prior to a septal lesion, blocked the expected hyperreactivity. Lesions localized to the medial or the lateral fibers of the fornix decreased the magnitude the duration of the expected hyperreactivity following septal lesions but did not block it. Lesions of the posterior hippocampus-entorhinal cortex had no reliable effect on the expected hyperreactivity after septal lesions. These data indicate that the appearance of hyperreactivity following a septal lesion depends upon a circuit involving the septum, precommissural fornix, anterior hippocampus, postcommissural fornix, and hypothalamus, and document an important functional relationship between the septum, anterior hippocampus, and hypothalamus.

References

Apr 1, 1970·Journal of Comparative and Physiological Psychology·B H Turner
Mar 1, 1966·Brain : a Journal of Neurology·G RaismanT P Powell
Jun 1, 1966·Brain : a Journal of Neurology·G Raisman

❮ Previous
Next ❯

Citations

Aug 1, 1978·European Journal of Pharmacology·R SchwarczJ T Coyle
Jan 1, 1979·Physiology & Behavior·D A Yutzey, J P Lieb
Jul 1, 1987·Pharmacology, Biochemistry, and Behavior·K RaffaeleJ McDonough
Jan 1, 1982·Neuroscience and Biobehavioral Reviews·D J Albert, M L Walsh
Jan 1, 1984·Neuroscience and Biobehavioral Reviews·D J Albert, M L Walsh
Jan 1, 1990·Behavioral and Neural Biology·A Poplawsky, R L Isaacson
Dec 1, 1980·Behavioral and Neural Biology·D J Albert, G L Chew
May 1, 1983·Behavioral and Neural Biology·A Poplawsky, R L Isaacson
Sep 1, 1983·Behavioral and Neural Biology·R L Isaacson, A Poplawsky
Feb 13, 2001·Behavioural Brain Research·K H ChanT L Davidson
May 1, 1985·The International Journal of Neuroscience·B S Chozick
Jan 13, 1978·Brain Research·D S OltonF H Gage
Jun 1, 1976·Behavioral Biology·F H Gage, D S Olton
Nov 1, 1981·Experimental Neurology·R G ThompsonF H Gage

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.