Hippocampal modifications in transient global amnesia

Revue neurologique
Peggy QuinetteF Viader

Abstract

Transient global amnesia (TGA) is an acute and transient syndrome with a remarkably stereotypical set of signs and symptoms. It is characterized by the abrupt onset (no forewarning) of massive episodic memory impairment, both anterograde and retrograde. Ever since it was first described, TGA has fascinated neurologists and other memory experts, and in recent years, there has been a surge of neuroimaging studies seeking to pin down the brain dysfunction responsible for it. Several pathophysiological hypotheses have been put forward, including the short-lived suggestion of an epileptic mechanism. All the available data indicate that the brain modifications are reversible, and that the mechanism behind TGA is of a functional nature. However, while diffusion-weighted imaging studies have clearly identified the hippocampus and, more specifically, the CA1 area, as the locus of brain modifications associated with TGA, researchers have yet to determine whether the origin of the mechanism is vascular or neurochemical. Spectroscopy may provide a means of settling this issue once and for all.

References

Oct 1, 1990·Journal of Neurology, Neurosurgery, and Psychiatry·J R Hodges, C P Warlow
Jun 1, 1994·Brain : a Journal of Neurology·J C BaronG Marchal
Apr 29, 1998·Journal of the Neurological Sciences·M ZorzonG Cazzato
Jun 24, 1998·Clinical Neurology and Neurosurgery·L C HsuH C Liu
Aug 26, 1998·Lancet·S L Lewis
Mar 27, 2001·The International Journal of Neuroscience·J KesslerW D Heiss
Dec 26, 2001·Brain Research. Brain Research Reviews·A Gorji
Feb 28, 2002·Neurology·Kevin S LaBarM Marsel Mesulam
Feb 14, 2003·European Neurology·N Maalikjy AkkawiA Padovani
Sep 17, 2004·Journal of Neurology·Barbara BorroniAlessandro Padovani
Feb 18, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·K WinbeckD Sander
Apr 5, 2005·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·L PantoniD Inzitari
Apr 13, 2005·Neurology·Tsutomu NakadaRobert T Knight
Jun 21, 2005·Lancet Neurology·Kerstin Sander, Dirk Sander
Aug 3, 2005·Medical Hypotheses·Ole Solheim, Tora Skeidsvoll
Mar 8, 2006·The European Journal of Neuroscience·Patrice QuintanaDominique Muller
May 4, 2006·Brain : a Journal of Neurology·Peggy QuinetteFrancis Eustache
Aug 19, 2007·Annals of Neurology·Thorsten BartschOlav Jansen
May 3, 2008·AJNR. American Journal of Neuroradiology·Y C WeonS Y Kim
Jun 28, 2008·Stroke; a Journal of Cerebral Circulation·Christian EnzingerFranz Fazekas
Jul 22, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C AgostiA Padovani
Jun 11, 2009·Journal of Clinical Neurology·Youngsoon YangJae Hyoung Kim
Feb 5, 2010·Lancet Neurology·Thorsten Bartsch, Günther Deuschl
Nov 30, 2010·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Audrey NoëlFrancis Eustache
Jan 5, 2011·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·I UttnerR Huber
Feb 15, 2011·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·M AuyeungK Y Lau
Oct 12, 2011·Proceedings of the National Academy of Sciences of the United States of America·Thorsten BartschGünther Deuschl
Jul 20, 2012·Stroke; a Journal of Cerebral Circulation·Claudio BaracchiniRenzo Manara
Sep 12, 2012·Archives of Neurology·Ricardo NitriniPaulo Caramelli
Jan 9, 2013·Nature Reviews. Neurology·Thorsten Bartsch, Christopher Butler
Apr 5, 2013·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Jungeun KimSangYun Kim
Dec 7, 2013·Stroke; a Journal of Cerebral Circulation·Atul ManglaHooman Kamel
Mar 14, 2014·Annals of Neurology·Michael PeerShahar Arzy
Aug 16, 2014·Case Reports in Neurological Medicine·Alejandro Gallardo-TurAdriá Arboix
Sep 16, 2014·Frontiers in Behavioral Neuroscience·Juliane DöhringThorsten Bartsch

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Citations

Jul 10, 2020·Neurology India·Marta Waliszewska-ProsolAnna Pokryszko-Dragan
Jun 19, 2019·Radiologia brasileira·Luiz de Abreu JuniorMaria Lucia Borri
Jan 4, 2021·Journal of Neurology·Ioannis LiampasEfthimios Dardiotis
Sep 14, 2021·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Matthew L WongNicole M Dubosh

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