Hippocampal remapping as hidden state inference.

ELife
Honi SandersSamuel J Gershman

Abstract

Cells in the hippocampus tuned to spatial location (place cells) typically change their tuning when an animal changes context, a phenomenon known as remapping. A fundamental challenge to understanding remapping is the fact that what counts as a ''context change'' has never been precisely defined. Furthermore, different remapping phenomena have been classified on the basis of how much the tuning changes after different types and degrees of context change, but the relationship between these variables is not clear. We address these ambiguities by formalizing remapping in terms of hidden state inference. According to this view, remapping does not directly reflect objective, observable properties of the environment, but rather subjective beliefs about the hidden state of the environment. We show how the hidden state framework can resolve a number of puzzles about the nature of remapping.

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Citations

Jan 21, 2021·Biological cybernetics·Chang Sub Kim
Oct 27, 2020·ELife·Henry Wp DalgleishMichael Häusser
Mar 24, 2021·Nature Neuroscience·Mark H Plitt, Lisa M Giocomo
Nov 27, 2020·Cell·Honi SandersIla Fiete
Apr 2, 2021·Frontiers in Psychology·Dragan M Svrakic, Charles F Zorumski
May 7, 2021·Brain and Neuroscience Advances·Charline TessereauTobias Bast
May 18, 2021·IScience·Diogo Santos-PataPaul F M J Verschure
Jun 19, 2021·Neuroscience and Biobehavioral Reviews·Linda Q YuMatthew R Nassar
May 25, 2021·ELife·Man Yi YimThibaud Taillefumier
Aug 5, 2021·Cell·Eric B Knudsen, Joni D Wallis
Aug 12, 2021·Nature Communications·Guo WanjiaBrice A Kuhl
Aug 25, 2021·Current Biology : CB·Hung-Tu ChenMatthijs A A van der Meer
Aug 29, 2021·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Anne G E Collins, Amitai Shenhav
Jan 16, 2022·Neuron·Nils NybergHugo J Spiers

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