Hippocampo-cerebellar theta band phase synchrony in rabbits

Neuroscience
Jan WikgrenMarkku Penttonen

Abstract

Hippocampal functioning, in the form of theta band oscillation, has been shown to modulate and predict cerebellar learning of which rabbit eyeblink conditioning is perhaps the most well-known example. The contribution of hippocampal neural activity to cerebellar learning is only possible if there is a functional connection between the two structures. Here, in the context of trace eyeblink conditioning, we show (1) that, in addition to the hippocampus, prominent theta oscillation also occurs in the cerebellum, and (2) that cerebellar theta oscillation is synchronized with that in the hippocampus. Further, the degree of phase synchrony (PS) increased both as a response to the conditioning stimuli and as a function of the relative power of hippocampal theta oscillation. However, the degree of PS did not change as a function of either training or learning nor did it predict learning rate as the hippocampal theta ratio did. Nevertheless, theta band synchronization might reflect the formation of transient neural assemblies between the hippocampus and the cerebellum. These findings help us understand how hippocampal function can affect eyeblink conditioning, during which the critical plasticity occurs in the cerebellum. Future studies...Continue Reading

References

Jun 16, 1978·Science·S D Berry, R F Thompson
Jan 1, 1986·Progress in Neurobiology·B H Bland
Dec 1, 2001·Neurobiology of Learning and Memory·S D Berry, M A Seager
Dec 1, 2001·Neurobiology of Learning and Memory·A V BeylinT J Shors
Jan 31, 2002·Proceedings of the National Academy of Sciences of the United States of America·Matthew A SeagerStephen D Berry
Feb 8, 2002·Neuron·György Buzsáki
Apr 2, 2005·Science·Jan-Mathijs SchoffelenPascal Fries
Apr 15, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·J Matias PalvaKai Kaila
Feb 10, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael J Kahana
Jan 11, 2008·Thalamus & Related Systems·Anton Sirota, György Buzsáki
Jan 18, 2008·Trends in Neurosciences·Diana S Woodruff-Pak, John F Disterhoft
May 24, 2008·Neuroscience and Biobehavioral Reviews·Paul Sauseng, Wolfgang Klimesch
Jul 10, 2008·Learning & Memory·Rony PazDenis Paré
Jun 3, 2009·Behavioral Neuroscience·Miriam S NokiaJan Wikgren
Aug 21, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Hana RosDavid A McCormick

❮ Previous
Next ❯

Citations

Sep 6, 2012·Experimental Brain Research·Marja LaasonenJan Wikgren
May 27, 2011·Neuroscience Bulletin·Lei Wang, Shen-Quan Liu
Oct 25, 2011·Science·Christelle RochefortLaure Rondi-Reig
Feb 25, 2011·Digestive Diseases and Sciences·Joaquin MerinoJorge-Luis Arias
Jan 7, 2016·Frontiers in Systems Neuroscience·Wilson Yu, Esther Krook-Magnuson
Apr 8, 2011·Current Opinion in Neurobiology·Joshua A Gordon
May 4, 2011·Behavioural Brain Research·T J ShorsM S Nokia
Mar 10, 2016·Frontiers in Psychology·Guy CheronBernard Dan
Oct 9, 2012·The European Journal of Neuroscience·Miriam S NokiaTracey J Shors
Jan 22, 2015·Developmental Psychobiology·Thomas C Harmon, John H Freeman
Nov 6, 2015·BioMed Research International·Tal Dotan Ben-SoussanAviva Berkovich-Ohana
Dec 18, 2014·Hippocampus·Shoai HattoriJohn F Disterhoft
Dec 17, 2014·Neuroscience and Biobehavioral Reviews·Bo HuJun Zhang
Dec 27, 2012·Neurobiology of Learning and Memory·Omid Shearkhani, Kaori Takehara-Nishiuchi
Aug 8, 2014·Frontiers in Integrative Neuroscience·Martin HitierPaul F Smith
Aug 24, 2013·Cerebral Cortex·Yoshiyuki OnukiYsbrand D Van der Werf
Sep 9, 2011·Journal of Neurophysiology·Emmanuelle CourtiolNathalie Buonviso
Jun 18, 2019·ELife·Thomas Charles WatsonLaure Rondi-Reig
Nov 5, 2019·The Journal of Physiology·Martha L Streng, Esther Krook-Magnuson
Oct 15, 2019·ELife·Zoé Christenson WickEsther Krook-Magnuson
May 18, 2020·Neuroscience and Biobehavioral Reviews·Derick H Lindquist
May 16, 2021·Neuroscience Bulletin·Wei-Wei ZhangHao Chen
Feb 10, 2020·Epilepsy & Behavior : E&B·Martha L Streng, Esther Krook-Magnuson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.

© 2022 Meta ULC. All rights reserved