Hirschsprung Disease beyond Infancy

Clinics in Colon and Rectal Surgery
Casey M Calkins

Abstract

Hirschsprung disease (HD) is a common cause of neonatal intestinal obstruction in which a variable segment of the distal intestinal tract lacks the normal enteric nervous system elements. Affected individuals present with varying degrees of obstructive symptoms, but today most patients are diagnosed within the first several months of life owing to the well-recognized symptoms and the ease of making the diagnosis by way of the bedside suction rectal biopsy. Thus, for the adult general or colorectal surgeon, the vast majority of patients who present for evaluation will have already undergone surgical treatment within the first year of life by a pediatric surgeon. Despite several safe operative interventions to treat patients with HD, the long-term results are far from perfect. These patients may reach adult life with ongoing defecation disorders that require a systematic evaluation by a multidisciplinary group that should be led by a surgeon with a thorough knowledge of HD operations and the potential problems. The evaluation of these patients will form the basis for the majority of this review-however, some patients manage to escape diagnosis beyond the infant and childhood period-and a section herein will briefly address the ca...Continue Reading

Citations

Nov 19, 2019·Journal of Pediatric Gastroenterology and Nutrition·Lucile EspesoIsabelle Talon
Nov 23, 2019·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Raj P KapurLusine Ambartsumyan
Nov 23, 2019·International Journal of Colorectal Disease·Devan SchlundAnuradha R Bhama
Jan 25, 2020·Journal of Pediatric Gastroenterology and Nutrition·Lucile EspesoIsabelle Talon
Nov 22, 2019·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Caitlin SmithRaj P Kapur
Apr 18, 2021·International Journal of Surgery Case Reports·Christopher GamezPeter M DeVito

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