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Histamine augments leukocyte adenosine 3',5'-monophosphate and blocks antigenic histamine release

Science

Aug 20, 1971

Helen C BourneLawrence M Lichtenstein

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Abstract

Extracellular histamine stimulates accumulation of adenosine 3',5'-monophosphate in human leukocytes and prevents antigenic release of histamine from cells of allergic donors. Both effects occur at histamine concentrations that can be achieved by antigenic release of the amine in vitro.

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  • Histamine augments leukocyte adenosine 3',5'-monophosphate and blocks antigenic histamine release

    Science

    Aug 20, 1971

    Helen C BourneLawrence M Lichtenstein

    PMID: 4105490

    DOI: 10.1126/science.173.3998.743

    Abstract

    Extracellular histamine stimulates accumulation of adenosine 3',5'-monophosphate in human leukocytes and prevents antigenic release of histamine from cells of allergic donors. Both effects occur at histamine concentrations that can be achieved by antigenic release of the amine in vitro.

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