PMID: 2879698Jan 1, 1986

Histamine-induced hyperphosphatemia and hypocalcemia in the laying hen

Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology
M C Cabrera-Saadoun, B Sauveur


The effects of histamine on plasma inorganic phosphorus (Pi) and total calcium values were studied in laying hens during egg formation and in non-laying hens. Histamine induced hyperphosphatemia and slight hypocalcemia during eggshell calcification, whereas the most pronounced hypocalcemia was observed during the early stages of egg formation. The histamine-induced hyperphosphatemia was completely inhibited by cimetidine but only partly by promethazine. However, the histamine-induced hypocalcemia was totally inhibited by cimetidine and promethazine.


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Jan 1, 1987·Comparative Biochemistry and Physiology. A, Comparative Physiology·M C Cabrera-Saadoun, B Sauveur
Jan 1, 1987·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·M C Cabrera-SaadounJ Gautron

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Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology
M C Cabrera-SaadounJ Gautron
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