Abstract
Five bacterial species considered to be potential pathogens in acute exacerbations of chronic bronchitis, cystic fibrosis, and pneumonia--Branhamella catarrhalis, Haemophilus parainfluenzae, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae--were evaluated for their potential to synthesise histamine in vitro. Bacterial species commonly isolated from infected sputum but generally not considered to be pathogenic--Enterobacteriacae, Neisseria pharyngis, coagulase negative staphylococci, alpha-haemolytic streptococci, and Candida albicans--were similarly studied. Of the "pathogens", the Gram negative species B catarrhalis, H parainfluenzae and Ps aeruginosa synthesised clinically important amounts of histamine; this was not the case for the Gram positive species S aureus and S pneumoniae. Of the "non-pathogenic" species, only the Enterobacteriacae, as a group, were found to synthesise clinically important amounts of histamine. These results show that some Gram negative bacteria, associated with acute exacerbations in respiratory infections, produce histamine and possibly other inflammatory mediators, which may contribute to their pathogenecity in the lower respiratory tract in vivo.
References
Sep 10, 1977·Lancet·L S TurnbullA B Kay
Dec 1, 1978·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·R C BoucherJ C Hogg
Jul 1, 1987·Clinical Allergy·M K ChurchS T Holgate
Jul 1, 1987·The Journal of Allergy and Clinical Immunology·A BrikE Lee
Jul 1, 1985·Somatic Cell and Molecular Genetics·D PattersonJ N Davidson
Mar 29, 1986·British Medical Journal·B D SheinmanS Tabaqchali
Nov 1, 1986·The Journal of Infectious Diseases·M M FarleyA Wright
Mar 1, 1986·Agents and Actions·B D SheinmanR J Davies
Apr 1, 1985·The American Review of Respiratory Disease·L A LaitinenT Haahtela
Aug 1, 1985·Thorax·P J ReesM N Maisey
Oct 11, 1985·Journal of Chromatography·J L DevaliaR J Davies
Jan 30, 1973·Biochemistry·P A Recsei, E E Snell
Oct 1, 1971·The Journal of Infectious Diseases·A M Lerner, M J Federman
Jan 1, 1971·Die Nahrung·C Ieniştea
Jul 15, 1970·European Journal of Pharmacology·M A BeavenW B Severs
Jan 1, 1982·Clinical Allergy·D H Bryant, A Pui
Aug 1, 1982·Applied and Environmental Microbiology·D H Yoshinaga, H A Frank
Mar 1, 1984·Clinical Allergy·I MoodleyR J Davies
Apr 1, 1982·The Journal of Hygiene·C K MurrayR J Gilbert
Citations
Aug 26, 1998·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·K McGregorT V Riley
Feb 8, 2002·Comparative Immunology, Microbiology and Infectious Diseases·Kevin W RubyMerlin L Kaeberle
Dec 1, 1993·Clinical Otolaryngology and Allied Sciences·M T CafferkeyM Walsh
Apr 1, 1993·Antimicrobial Agents and Chemotherapy·J E FowerakerP M Hawkey
Jul 14, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M Cafferkey
Aug 6, 1999·Journal of Chemotherapy·S UmutM Akman
Apr 3, 2014·Gut Microbes·Mark Lyte
Sep 1, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S R RutgersD S Postma
May 18, 2017·American Journal of Speech-language Pathology·Karen A Erickson
Sep 10, 2015·Scientific Reports·Ajay KrishnamurthyNikhil Koratkar
Mar 15, 1997·Medizinische Klinik·W Cullmann
Feb 24, 2017·Probiotics and Antimicrobial Proteins·Alexander V OleskinVladimir S Rogovsky
Mar 7, 2019·Frontiers in Genetics·Ting-Ting HuangShao-Hua Hu
Nov 22, 2019·Frontiers in Neuroscience·Susan Westfall, Giulio Maria Pasinetti
May 27, 2016·Microbiology Spectrum·Mark Lyte
Oct 1, 1990·Clinical Microbiology Reviews·B W Catlin
May 1, 1993·Respiratory Medicine·R J GaffneyM T Cafferkey