PMID: 2499609May 1, 1989Paper

Histamine synthesis by respiratory tract micro-organisms: possible role in pathogenicity

Journal of Clinical Pathology
J L DevaliaR J Davies

Abstract

Five bacterial species considered to be potential pathogens in acute exacerbations of chronic bronchitis, cystic fibrosis, and pneumonia--Branhamella catarrhalis, Haemophilus parainfluenzae, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae--were evaluated for their potential to synthesise histamine in vitro. Bacterial species commonly isolated from infected sputum but generally not considered to be pathogenic--Enterobacteriacae, Neisseria pharyngis, coagulase negative staphylococci, alpha-haemolytic streptococci, and Candida albicans--were similarly studied. Of the "pathogens", the Gram negative species B catarrhalis, H parainfluenzae and Ps aeruginosa synthesised clinically important amounts of histamine; this was not the case for the Gram positive species S aureus and S pneumoniae. Of the "non-pathogenic" species, only the Enterobacteriacae, as a group, were found to synthesise clinically important amounts of histamine. These results show that some Gram negative bacteria, associated with acute exacerbations in respiratory infections, produce histamine and possibly other inflammatory mediators, which may contribute to their pathogenecity in the lower respiratory tract in vivo.

References

Dec 1, 1978·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·R C BoucherJ C Hogg
Mar 29, 1986·British Medical Journal·B D SheinmanS Tabaqchali
Mar 1, 1986·Agents and Actions·B D SheinmanR J Davies
Apr 1, 1985·The American Review of Respiratory Disease·L A LaitinenT Haahtela
Jan 30, 1973·Biochemistry·P A Recsei, E E Snell
Oct 1, 1971·The Journal of Infectious Diseases·A M Lerner, M J Federman
Jul 15, 1970·European Journal of Pharmacology·M A BeavenW B Severs
Aug 1, 1982·Applied and Environmental Microbiology·D H Yoshinaga, H A Frank
Apr 1, 1982·The Journal of Hygiene·C K MurrayR J Gilbert

❮ Previous
Next ❯

Citations

Aug 26, 1998·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·K McGregorT V Riley
Feb 8, 2002·Comparative Immunology, Microbiology and Infectious Diseases·Kevin W RubyMerlin L Kaeberle
Dec 1, 1993·Clinical Otolaryngology and Allied Sciences·M T CafferkeyM Walsh
Jul 14, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M Cafferkey
Sep 1, 1999·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S R RutgersD S Postma
May 18, 2017·American Journal of Speech-language Pathology·Karen A Erickson
Sep 10, 2015·Scientific Reports·Ajay KrishnamurthyNikhil Koratkar
Mar 15, 1997·Medizinische Klinik·W Cullmann
Feb 24, 2017·Probiotics and Antimicrobial Proteins·Alexander V OleskinVladimir S Rogovsky
Mar 7, 2019·Frontiers in Genetics·Ting-Ting HuangShao-Hua Hu
Nov 22, 2019·Frontiers in Neuroscience·Susan Westfall, Giulio Maria Pasinetti
May 27, 2016·Microbiology Spectrum·Mark Lyte
Oct 1, 1990·Clinical Microbiology Reviews·B W Catlin
May 1, 1993·Respiratory Medicine·R J GaffneyM T Cafferkey

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Related Papers

Handbook of Clinical Neurology
Michael R Irwin, Matthias Rothermundt
Proceedings of the Society for Experimental Biology and Medicine
D F SchaferE A Jones
Journal of Bacteriology
Vic NorrisAndrew T Gewirtz
© 2022 Meta ULC. All rights reserved