PMID: 5919749Nov 25, 1966

Histamine synthesis in man: inhibition by 4-bromo-3-hydroxybenzyloxyamine

R J Levine


Oral administration of 4-bromo-3-hydroxybenzyloxyamine to normal humans resulted in decreased urinary excretion of histamine; the normal increase in urinary levels of histamine after oral histidine loading was prevented. In two patients having systemic mastocytosis, additional evidence of inhibition of biosynthesis of histamine included marked reduction in symptoms attributed to histamine, and prevention of symptomatic exacerbation associated with histidine loading.


May 1, 1970·The American Journal of Digestive Diseases·R J LevineT Hersh
Mar 1, 1971·Canadian Anaesthetists' Society Journal·D Lee, D L Johnson
Oct 1, 1969·Biochemical Pharmacology·K O Wustrack, R J Levine
Dec 24, 1970·The New England Journal of Medicine·R T Keller, H P Roth
Jul 1, 1971·The Journal of Pharmacy and Pharmacology·H Mesch, K Sewing
May 1, 1972·The Journal of Pharmacy and Pharmacology·R LAZARE, P A Watson
Dec 1, 1970·Journal of Pharmaceutical Sciences·G H HamorG W Fisch
Sep 30, 1969·Annals of the New York Academy of Sciences·R J Levine, W W Noll
Jun 1, 1979·Clinical and Experimental Dermatology·M W Greaves
May 24, 1973·Zeitschrift für Rechtsmedizin. Journal of legal medicine·I G FazekasA Basch
Nov 1, 1968·Acta Medica Scandinavica·B BergT White
Aug 1, 1968·Acta Physiologica Scandinavica·S A Slorach, B Uvnäs

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