Histiocytic disorders of the chest: imaging findings

Radiographics : a Review Publication of the Radiological Society of North America, Inc
Jitesh AhujaJ David Godwin

Abstract

Histiocytic disorders of the chest comprise a broad spectrum of diseases. The lungs may be involved in isolation or as part of systemic disease. Some of these disorders are primary and have unknown etiology, and others result from a histiocytic response to a known cause. Among primary histiocytic disorders, pulmonary Langerhans cell histiocytosis (PLCH) is the most common; others include Erdheim-Chester disease and Rosai-Dorfman disease. Adult PLCH occurs almost exclusively in adults aged 20-40 years who smoke. Pediatric PLCH is extremely rare and typically occurs as part of multisystemic disease. Erdheim-Chester disease affects middle-aged and older adults; thoracic involvement usually occurs as part of systemic disease. Rosai-Dorfman disease affects children and young adults and manifests as painless cervical lymphadenopathy. Examples of secondary histiocytic disorders are storage diseases such as Gaucher disease, Niemann-Pick disease, and Fabry disease; pneumoconiosis such as silicosis and coal workers' pneumoconiosis; and infections such as Whipple disease and malakoplakia. These disorders are characterized at histopathologic examination on the basis of infiltration of alveoli or the pulmonary interstitium by histiocytes, w...Continue Reading

References

May 11, 1992·Radiographics : a Review Publication of the Radiological Society of North America, Inc·E L KulwiecT E King
Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·F BonettiD M Knowles
Nov 28, 1987·British Medical Journal·A VellodiK Hugh-Jones
Feb 1, 1972·The Journal of Pathology·M I SkikneI Webster
Jul 21, 1994·The New England Journal of Medicine·C L WillmanD G Gilliland
Mar 1, 1996·Thorax·C A KellyJ Rawlinson
Nov 1, 1996·Journal of Computer Assisted Tomography·G R FerrettiM Coulomb
Jan 1, 1997·Current Opinion in Hematology·E Beutler
Mar 1, 1997·Radiographics : a Review Publication of the Radiological Society of North America, Inc·T E HartmanN L Müller
Mar 1, 1997·American Journal of Respiratory and Critical Care Medicine·L K BrownR J Desnick
May 1, 1997·AJR. American Journal of Roentgenology·J M SeelyN L Müller
Aug 7, 1998·AJR. American Journal of Roentgenology·S M KubaskaS B Keel
Oct 2, 1998·Clinical Imaging·N A Yassa, A G Wilcox
Jan 5, 2000·American Journal of Respiratory and Critical Care Medicine·M FartoukhG Simonneau
Feb 5, 2000·AJR. American Journal of Roentgenology·S J CopleyD M Hansell
May 2, 2000·AJR. American Journal of Roentgenology·K H WittenbergJ L Myers
Jul 6, 2000·The New England Journal of Medicine·R VassalloA H Limper
Feb 24, 2001·The American Journal of the Medical Sciences·R D ShamburekB R Gochuico
Aug 9, 2001·QJM : Monthly Journal of the Association of Physicians·O GoiteinA Zimran
Nov 16, 2001·The British Journal of Radiology·F DuchateauE Coche
Jan 10, 2002·American Journal of Respiratory and Critical Care Medicine·Andrew G NicholsonCliff Morgan
Feb 15, 2002·The New England Journal of Medicine·Robert VassalloAndrew H Limper
Aug 21, 2002·The American Journal of the Medical Sciences·Anu GuptaJames E McGuigan
Feb 20, 2003·AJR. American Journal of Roentgenology·Mitsuhiro KoyamaNestor L Müller
Dec 4, 2003·Human Pathology·N Paul OhoriKevin Kane
Jan 24, 2004·Pediatric Radiology·Sabine SchmidtFrançois Gudinchet
Mar 10, 2004·Chest·Jose L MendezJay H Ryu
Oct 27, 2004·AJR. American Journal of Roentgenology·Elisabeth DionPhilippe A Grenier
Jun 16, 2005·Respirology : Official Journal of the Asian Pacific Society of Respirology·Jae H ChungYoung S Kim
Jun 22, 2005·Seminars in Immunology·Hendrik Jan de HeerBart N Lambrecht
Nov 9, 2005·Pediatric Blood & Cancer·Isaac OdameSheila Weitzman
Mar 24, 2006·AJR. American Journal of Roentgenology·Olivier LidoveJean-Pierre Laissy
Apr 21, 2006·Histopathology·A G NicholsonS Lantuejoul
Jun 15, 2006·The European Respiratory Journal·A Tazi
Sep 19, 2006·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Christine M EngWilliam R Wilcox
Sep 28, 2006·Brain : a Journal of Neurology·Mathieu SévinFrédéric Sedel

❮ Previous
Next ❯

Citations

May 12, 2016·Lung·Felipe Mussi von RankeEdson Marchiori
May 18, 2016·Reumatología clinica·Pablo Antonio Zurita PradaMaria Henar Borrego Pintado
Feb 1, 2017·AJR. American Journal of Roentgenology·Winnie A MarChristine O Menias
Jun 8, 2018·QJM : Monthly Journal of the Association of Physicians·S Stone, D Lynch
Jan 18, 2018·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Heloisa Maria Pereira FreitasEdson Marchiori
Jan 9, 2020·The Clinical Respiratory Journal·Aleksandra Jezela-StanekAnna Tylki-Szymańska
Jun 6, 2020·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Muhammad NaeemSanjeev Bhalla
Jan 18, 2019·International Journal of Molecular Sciences·Paola FaverioAndrea Biondi
Aug 31, 2019·Annals of the American Thoracic Society·Amanda Romesberg, Marianna Zagurovskaya
Jun 1, 2018·Case Reports in Hematology·Andrew R OrrPallavi Kumar
Feb 20, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Kenneth N Huynh, Ba D Nguyen
Feb 24, 2020·Molecular Genetics and Metabolism·Eline C B EskesCarla E M Hollak
Jun 4, 2021·Survey of Ophthalmology·Menelaos KanakisIlias Georgalas

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.