Jan 1, 1977

Histochemical and ultrastructural study of the parafollicular (C) cells in the thyroid of the gerbil, Meriones unguiculatus

Acta Anatomica
S P Kapur


A histochemical and electron-microscopic study has been done on the parafollicular (C) cells of the thyroid in the gerbil. Histochemical tests revealed the characteristic presence of alpha-glycerophosphoric dehydrogenase and the presence of phenolic groups and indoleamines. Acid phosphatase levels were similar to those observed in the apical cytoplasm of the follicular cells. Electron microscopy revealed characteristic presence of noncisternal rough endoplasmic reticulum, well-developed Golgi apparatus, numerous prosecretory granules and a few electrondense mature secretory granules. Most characteristic of these cells was the presence of numerous, large, electron-lucent vesicles which often were packed in the cytoplasmic processes that were located subjacent to the follicular cells and close to the blood capillaries. Significance of these histochemical and ultrastructural findings is emphasized particularly in regard to the presence of monoamines and their possible role in the release of calcitonin and thyroxin.

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Mentioned in this Paper

CALCA gene
Acid Phosphatase
Calcitonin preparation
Golgi Apparatus
Glycerol-3-Phosphate Dehydrogenase
Thyroid Diseases

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