Sep 8, 1989

Histochemical demonstration of zinc in the hippocampal region of the domestic pig: I. Entorhinal area, parasubiculum, and presubiculum

The Journal of Comparative Neurology
I E Holm, F A Geneser


A detailed description is given of the distribution of zinc in three areas of the domestic pig hippocampal region, viz., the entorhinal area, the parasubiculum, and the presubiculum. Zinc was demonstrated histochemically with use of the Neo-Timm method, a recent modification of the sulphide silver procedure. Each of the studied areas showed a distinctly stratified staining pattern, which has been correlated in detail to fields and layers defined on the basis of cyto- and fibroarchitecture, providing a combined chemo- and cytoarchitectonic map. The staining was primarily confined to the neuropil, although stained nerve cell bodies were encountered in all three parts of the hippocampal region. Two main subfields were identified in the entorhinal area that have been designated pars medialis and pars lateralis, in accordance with their topographical positions, but both the cytoarchitecture and Neo-Timm staining pattern are indicative of further subdivision. In pars medialis, the deep half of layer I, the interstices between the stellate cell bodies in layer II, and layer III were medium to heavily stained, whereas layer IV stained weakly. Layers V-VI were slightly darker than layer IV and were inseparable on the basis of the Neo-Ti...Continue Reading

Mentioned in this Paper

Synaptic Vesicles
Central Lobule of Cerebellum
Internal Granular Layer
Thiel-Behnke Corneal Dystrophy
Sus scrofa domestica
Stellate Cell

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