Histoid leprosy - unusual presentation

International Journal of Dermatology
S Pradeep NairGomathy Mini

Abstract

A 39-year-old man presented with a chronic nonhealing toe ulcer and multiple skin-colored papules on the back, arms, and knees. From an initial small erosion, the toe lesion ulcerated over a 1.5-year period, while the papules progressed over a 6-month period, first appearing on the back and then spreading to the arms and knees. The past medical and family history were non-contributory. Pertinent findings included the aforementioned well-defined, asymmetric, shiny papules (Fig. 1). There were multiple, discrete, erythematous, pedunculated, tumor-like masses of various sizes over the right thigh (Fig. 2) and a well-defined 4 cm x 3 cm ulcer on the second toe of the left foot, the floor of which was covered by necrotic slough. There was distal loss of sensation to temperature, touch, and pain. The greater auricular, ulnar, radial cutaneous and common peroneal nerves were thickened bilaterally, but non-tender. A clinical diagnosis of histoid leprosy was made. The differential diagnosis for the tumor-like thigh masses included dermatofibroma, neurofibroma, and Kaposi's sarcoma. The hemogram, liver/renal function tests, chest X-ray, and abdominal ultrasound were normal. Human immunodeficiency virus enzyme-linked immunosorbent assay (...Continue Reading

References

Jan 1, 1988·Dermatologica·V N Sehgal, G Srivastava

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Citations

Jan 1, 2009·BMJ Case Reports·Geok Chin TanRajadurai Pathmanathan
Dec 17, 2014·Indian Dermatology Online Journal·Pradeep S Nair
Jun 23, 2009·International Journal of Dermatology·Virendra N SehgalPullabatla V S Prasad
Apr 18, 2013·International Journal of Dermatology·Sukumaran Pradeep Nair, Gopinathan Nanda Kumar
Nov 13, 2015·Anais Brasileiros De Dermatologia·Pedro Jose Secchin de AndradeJosé Augusto da Costa Nery
Jan 26, 2018·Journal of Clinical Pathology·Maroun M SfeirCatherine B Small
Mar 23, 2017·International Journal of Dermatology·Mahesh MathurRoshani Wagle
May 20, 2021·The American Journal of Dermatopathology·Eduardo Rozas-MuñozAnna Mozos

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