Histologic analysis of healing after tooth extraction with ridge preservation using mineralized human bone allograft

Journal of Periodontology
Tina M Beck, Brian L Mealey

Abstract

Ridge preservation was developed as a therapy to prevent severe bone resorption after tooth extraction. The purpose of this study is to determine if there is any difference in the amount of new bone formation ≈3 months after extraction and ridge preservation compared to that after ≈6 months. Minimally traumatic extraction with ridge preservation using mineralized human bone allograft was performed at 38 single-rooted tooth sites in 33 subjects. Sixteen sites healed for an average of 14 weeks (early healing), whereas 22 sites were allowed to heal for an average of 27 weeks (delayed healing) before harvesting bone core samples. Histomorphometric analysis was performed to determine the percent of new bone formation, residual graft particles, and connective tissue/non-mineralized structures for each site. All specimens showed evidence of new bone formation, with most of the residual graft particles surrounded intimately by woven bone. No statistically significant differences in the amount of newly formed bone or residual graft particles were found between the two groups. Overall, the early healing group demonstrated a mean of 45.8% new bone, 14.6% residual graft material, and 39.6% connective tissue/non-mineralized tissue. The dela...Continue Reading

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Citations

Sep 16, 2015·Journal of Oral Science·Tyman P LovelessFaisal A Quereshy
Apr 2, 2014·Clinical Oral Implants Research·Antonio BaroneUgo Covani
Jul 2, 2015·Clinical Implant Dentistry and Related Research·Maximillian WillenbacherEik Schiegnitz
Aug 4, 2016·Clinical Oral Implants Research·Rafael Delgado-RuizJosé Luis Calvo-Guirado
Jul 28, 2016·Clinical Oral Implants Research·Neil MacBethNikos Mardas
Jul 26, 2019·Platelets·Tomas PuidokasGintaras Juodzbalys
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Oct 28, 2015·Implant Dentistry·Luis BrandamGeorgios E Romanos
Aug 1, 2017·Clinical Advances in Periodontics·Julio A CarrionVincent J Iacono
Jan 6, 2021·Clinical and Experimental Dental Research·Constanze SteinerAngelines Gasser
Apr 16, 2021·Journal of Dental Sciences·Ngoc Bao VuPasutha Thunyakitpisal
Jul 25, 2021·International Journal of Environmental Research and Public Health·Vasilena IvanovaEitan Mijiritsky
Aug 8, 2021·Journal of Clinical Medicine·Marta Vallecillo-RivasMaría Victoria Olmedo-Gaya
Aug 8, 2020·Journal of Oral Biology and Craniofacial Research·Ankit SharmaSuday Rajurkar

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