PMID: 6540379Aug 1, 1984Paper

Histologic evidence for death of cortical neurons after spinal cord transection

Neurology
E R FeringaH L Vahlsing

Abstract

Dying cortical neurons, identified by standard histologic criteria, were observed in the rat sensory/motor cortex after spinal cord transection. The peak incidence of these changes was 10 weeks after injury. At that time, spinal-cord-injured animals showed 10 times as many abnormal cells as were found in matched controls (p less than or equal to 0.05). Dying cells were found in the same anatomic location as corticospinal neurons axotomized by the experimental injury, and at the expected time after injury. The survival of corticospinal neurons in these young adult rats may be dependent on obtaining a crucial input from an appropriate target cell (neuron).

Citations

Oct 31, 2000·The Journal of Comparative Neurology·A M PastorR R de La Cruz
Apr 1, 1988·Experimental Neurology·E R FeringaJ N Pruitt
Aug 5, 1985·Neuroscience Letters·E R Feringa, H L Vahlsing
Mar 4, 2008·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Keisuke IshizawaTakanori Hirose
Mar 1, 1989·Journal of Neurology, Neurosurgery, and Psychiatry·T YamamotoT Imai
Jun 10, 2003·The Journal of Comparative Neurology·Bryan C HainsStephen G Waxman
Jul 18, 2008·The Journal of Comparative Neurology·M I ShifmanM E Selzer
May 1, 1986·Experimental Neurology·E R Feringa, H L Vahlsing
Nov 3, 2004·Brain Research·Adrian Philip CrawleyDavid John Mikulis
Sep 1, 1984·Journal of Neurology, Neurosurgery, and Psychiatry·E R FeringaR C Dauser
Jun 13, 2000·Journal of Neuropathology and Experimental Neurology·K IshizawaD W Dickson
Oct 17, 2020·Neural Regeneration Research·Ke-Xue ZhangJi-Ying Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.