Histologic evidence for small-vessel coronary artery disease in patients with angina pectoris and patent large coronary arteries

Circulation
M MosseriY Hasin

Abstract

We studied six patients who suffered from angina pectoris but had angiographically patent major coronary arteries. Two of the patients suffered also from congestive heart failure. Three patients had supraventricular tachyarrhythmias. Three patients had conduction disturbances. During coronary angiography the patients had significantly reduced flow velocity of angiographic contrast medium compared with that in a control group. Echocardiographic and Doppler flow studies showed a tendency for symmetrical thickening of the left ventricular wall, enlargement of the right ventricle, and reduced compliance of both ventricles. Right ventricular endomyocardial biopsy revealed pathologic small coronary arteries with fibromuscular hyperplasia, hypertrophy of the media, myointimal proliferation, and endothelial degeneration. Capillaries had swollen endothelial cells encroaching on the lumen. Myocardial hypertrophy, lipofuscin deposition, and patchy fibrosis were also observed. These cases show that small-vessel coronary artery disease can cause classic angina pectoris. The diagnosis can be suspected when the coronary angiogram shows large patent arteries with slow flow of the angiographic contrast medium and it can be confirmed by endomyoc...Continue Reading

References

Jun 1, 1975·Circulation·T N James, T K Marshall
Jan 25, 1985·The American Journal of Cardiology·R O CannonS E Epstein
Jan 1, 1972·Virchows Archiv. A: Pathology. Pathologische Anatomie·H L Ratcliffe, E Redfield
Sep 1, 1964·Archives of Internal Medicine·T N JAMES, I J SCHATZ
Sep 1, 1962·American Heart Journal·B M MORE, S C SOMMERS

❮ Previous
Next ❯

Citations

Sep 12, 2012·Archives of Ophthalmology·Juan E GrunwaldUNKNOWN CRIC Study Group
Jun 1, 1989·Cardiovascular Drugs and Therapy·A H Henderson
Jan 24, 2009·Heart and Vessels·Hatice SelcukAli Sasmaz
May 26, 2009·Heart and Vessels·Ramazan TopsakalAli Ergin
Jan 6, 2011·Heart and Vessels·Shuang XiaQiang She
Jul 15, 2005·The International Journal of Cardiovascular Imaging·Emre AksakalMahmut Sahin
Jun 6, 2009·Journal of Thrombosis and Thrombolysis·Turgay CelikErsoy Isik
Mar 20, 2001·Current Atherosclerosis Reports·O AliH Ventura
Feb 12, 2008·Advances in Therapy·Yasar EnliHavane Enli
Aug 1, 1995·International Journal of Cardiology·G Y LipS P Singh
Jan 1, 1989·Journal of the American College of Cardiology·J M Nicklas, S J Gips
Jul 1, 1992·Journal of the American College of Cardiology·G SütschH P Krayenbühl
Oct 1, 1993·Journal of the American College of Cardiology·M BikkinaD Levy
May 1, 1995·Journal of the American College of Cardiology·J G WiedermannM Apfelbaum
Feb 1, 1994·Journal of the American College of Cardiology·A ChauhanP M Schofield
Mar 16, 2001·The American Journal of Cardiology·N KurtogluI Dindar
Aug 1, 1988·The American Journal of Medicine·P TellierJ P Battesti
Nov 28, 1987·Lancet
May 4, 2001·International Journal of Cardiology·B YaymaciI Dindar
Nov 5, 1999·International Journal of Cardiology·H D DanenbergD Gilon
Feb 1, 1991·Journal of the American College of Cardiology·A MaseriT Crake
May 1, 1991·Journal of the American College of Cardiology·J K GhaliY L Liao
Apr 6, 2002·Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology·Jeou-Jong ShyuSi-Kwang Liu
Aug 4, 2007·International Journal of Impotence Research·Z NurkalemM Eren
Jan 15, 2010·European Heart Journal·Joaquin LucenaCristina Basso
Jan 1, 1991·Diabetic Medicine : a Journal of the British Diabetic Association·A DoriaG Crepaldi
Jun 1, 1993·British Heart Journal·A ChauhanP M Schofield
Oct 1, 1993·British Heart Journal·A ChauhanP M Schofield
Jan 1, 1991·Postgraduate Medical Journal·M E Bourke, D L Patterson
May 31, 2012·Cardiology Research and Practice·Muhammad A ChaudhryRalph Lazzara

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.