Histologic study of the ocular lesions in multiple endocrine neoplasia syndrome type IIb

American Journal of Ophthalmology
B SpectorS A Wells

Abstract

We studied the clinical and histopathologic findings in the eyes of two patients with multiple endocrine neoplasia type IIb. A prominent clinical feature of this condition is enlarged nonmyelinated corneal nerves composed of bundles of axons associated with Schwann cells. Prominent corneal nerves within an otherwise normal corneal stroma are an important clinical feature of multiple endocrine neoplasia type IIb. Because of this, ophthalmologists are in a position to make an early diagnosis and hence to recommend diagnostic procedures and treatment for the associated potentially fatal medullary carcinoma of the thyroid and pheochromocytomas.

References

Sep 30, 1977·Documenta Ophthalmologica. Advances in Ophthalmology·N M Schweitzer, B A van der Pol
Jan 1, 1966·The Journal of Pathology and Bacteriology·E D Williams, D J Pollock
Dec 3, 1970·The New England Journal of Medicine·S B BaylinA Sjoerdsma
Oct 1, 1928·The British Journal of Ophthalmology·M L Hine, R B Wyatt

❮ Previous
Next ❯

Citations

Mar 15, 1991·American Journal of Ophthalmology·S KinoshitaS Takai
Sep 7, 2016·International Journal of Endocrine Oncology·Diala El-MaoucheStephen J Marx
Nov 22, 2011·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Yu UsamiSatoru Toyosawa
Jul 30, 2004·Clinical & Experimental Ophthalmology·Douglas G ParkerBrett A O'Donnell
Apr 2, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M C HerwigE Bierhoff
Feb 24, 2001·International Ophthalmology Clinics·S K Kim, C H Dohlman
Jun 5, 2001·Ophthalmic Plastic and Reconstructive Surgery·J M Jacobs, M J Hawes
Oct 1, 1988·Journal of Medical Genetics·J P Fryns, K Chrzanowska

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Autoimmune Polyendocrine Syndromes

This feed focuses on a rare genetic condition called Autoimmune Polyendocrine Syndromes, which are characterized by autoantibodies against multiple endocrine organs. This can lead to Type I Diabetes.

Related Papers

American Journal of Ophthalmology
F C Riley, D M Robertson
Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
M J CorreiaJ L Tuna
© 2021 Meta ULC. All rights reserved