Histological analysis of aortic dissections following previous cardiovascular surgery

Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology
Adriana LukJagdish Butany

Abstract

Aortic dissections have been reported as a rare complication post-cardiovascular surgery due to areas of cross clamping, suture lines and cannulation sites as locations for peri-operative injury. This study aimed to review the histological features of aortic tissues of 11 patients with aortic dissections who underwent previous cardiovascular surgery and to identify evidence of trauma within the area of surgery. A review of our records from January 2000 to July 2005 showed that 11 patients had developed a postoperative aortic dissection. Surgically excised aortic tissues were obtained either at surgery or at autopsy for further gross and histological analysis. Clinical records were also reviewed for relevant history. The mean age of the 11 patients in this study was 60.1+/-12.5 years. The year of index surgery for all patients was between 1960 and 2005, and the interval between index surgery and admission for re-operation was 13.8+/-12.9 years (range, 1 day to 45 years). Five patients (45%) demonstrated aortic intimal thickening, two of which showed evidence of atherosclerotic plaques. Three (27%) exhibited cystic medial change. All cases showed mild to moderate medial changes near or at the site of traumatic injury, as demonstr...Continue Reading

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Citations

Sep 16, 2008·Ageing Research Reviews·Fang LuoRu-Tai Hui
Jan 3, 2013·The Plant Journal : for Cell and Molecular Biology·Cécile RibotThomas Kroj
Dec 7, 2011·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Jaroslav BenedikHeinz Jakob
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Apr 8, 2021·The Journal of International Medical Research·Chenjun HanJian Zhou
Oct 4, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Harish RamEugene A Hessel

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