Histological and mechanical comparison of hydroxyapatite-coated cobalt-chrome and titanium implants in the rabbit femur

Journal of Applied Biomaterials : an Official Journal of the Society for Biomaterials
R J FriedmanR A Draughn

Abstract

The purpose of this study was to compare hydroxyapatite (HA)-coated titanium (Ti) and HA-coated cobalt-chrome (CoCr) implants in the distal femur of the rabbit by evaluating bone apposition and interfacial shear strength. Bilateral cylindrical implants with a plasma sprayed 50-microns thick HA coating were press-fit into the metaphyseal cancellous bone of the lateral femoral condyles in a transverse fashion, and the animals were sacrificed at 2, 4, and 8 weeks postimplantation. Mechanical strength of the interface between HA and bone was measured using the pushout method. For histologic analysis, the fractional linear extent of bone apposition was quantitated. No differences were found in the interfacial shear strength between the Ti and CoCr at any time period. The amount of bone apposition increased significantly at each time interval for both substrate metals, but there were no significant differences between the two substrates at any of the time periods studied. The HA-coated CoCr implants performed in a similar manner to the HA-coated Ti implants, both mechanically and histologically, suggesting that HA-coated CoCr implants deserve further study as a viable alternative to Ti for the biological fixation of total joint compo...Continue Reading

References

Mar 1, 1992·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·K SøballeC Bünger
Aug 1, 1992·Journal of Biomedical Materials Research·S D CookJ F Kay
Jan 1, 1992·Journal of Biomedical Materials Research·W J DhertP M Rozing
Sep 1, 1991·The Journal of Bone and Joint Surgery. British Volume·D C HardyP E Delince
Sep 1, 1991·The Journal of Bone and Joint Surgery. British Volume·R J Furlong, J F Osborn
Aug 1, 1991·Journal of Biomedical Materials Research·J A JansenK de Groot
Jul 1, 1990·The Journal of the American Dental Association·J N KentD J Misiek
Jan 1, 1989·The Journal of Arthroplasty·S D CookR J Haddad
Jan 1, 1989·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·J C KellerE St Mary
Mar 1, 1989·The Journal of Bone and Joint Surgery. British Volume·H OonishiY Ukon
May 1, 1980·Journal of Biomedical Materials Research·P DucheyneJ C Mulier
Feb 1, 1995·Journal of Biomedical Materials Research·J E Dalton, S D Cook
Apr 1, 1993·Journal of Biomedical Materials Research·C C VerheyenP M Rozing

❮ Previous
Next ❯

Citations

Dec 30, 1999·Biomaterials·D M FerrisR F Valentini
Feb 4, 2010·Journal of Biomedical Materials Research. Part a·Stig S JakobsenKjeld Soballe
May 2, 2006·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·John A LeupoldLangdon A Hartsock
Nov 8, 2006·Biotechnology and Bioengineering·Françoise PeyrinRoberta Martinetti
Nov 20, 1998·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Y H AnT W Bauer
May 7, 2009·Nanotechnology·Timothy RuckhKetul C Popat
May 27, 2003·Journal of Dental Research·Y YangJ L Ong
Jul 28, 2004·International Review of Psychiatry·L Burke
May 10, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Holly J MartinKeisha B Walters
Apr 20, 2021·Journal of the Mechanical Behavior of Biomedical Materials·H Q LiX Y Fang
May 20, 2015·International Journal of Biological Macromolecules·R A FarghaliH K A Elhakim

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.