Histological changes associated with long-term urethral stents

British Journal of Urology
D M BaileyP J Shah

Abstract

To assess the histological changes found in patients with long-term external sphincter, prostatic and urethral stents. Eighteen patients with long-term stents (mean time since insertion 3.5 years) were investigated. Three had external sphincter stents for detrusor-sphincter dyssynergia secondary to spinal injury, eight had prostatic stents for obstruction secondary to benign prostatic hyperplasia and seven had urethral stents for recurrent strictures. Nine stents were occluded at investigation, of which seven were entirely removed. The mucosae overlying the remaining two were biopsied, as were mucosae over the nine patent stents, at urethroscopy. The changes observed included polypoid hyperplasia (11 of 18 patients) between and around the stent mesh wires, nonkeratinizing squamous metaplasia (two) or hyperkeratotic squamous metaplasia (seven), chronic inflammation (15) with prominent plasma cell infiltrates (11), variable foreign-body granuloma (two) and microabscess formation (five), usually associated with clefts formed around the stent wires (three of five). Stents become incorporated into the urethral wall by a process of polypoid hyperplasia through the stent mesh, with at least focal covering of the stent in most cases, a...Continue Reading

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Citations

Apr 17, 2007·Cardiovascular and Interventional Radiology·Verónica CrisóstomoJesús Usón-Gargallo
Jan 6, 2009·PloS One·Mubashir HanifMaria Eriksson
Jun 21, 2005·European Journal of Pain : EJP·Vincent J MieleJulian E Bailes
Aug 29, 2016·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·X MatillonA Ruffion
May 3, 2006·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Carlos A CuryFernando Batigalia
May 28, 2005·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Elsa F VelazquezAntonio L Cubilla
Dec 7, 2007·European Urology·Christopher R Chapple, Saurabh Bhargava
Mar 9, 2007·Annals of Saudi Medicine·A H Kardar, E Lindstedt

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