Jun 1, 1977

Histological changes in the canine stomach following massive electron beam irradiation

A Minami


The histologic changes induced by irradiation of the stomachs of dogs were examined one hour to nine months after irradiation. The irradiated area of the stomach progressed to ulcer formation by way of hyperemia and erosion; on the other hand, there were simultaneous signs of recovery. Regenerating epithelium appeared during the first week and migrated from the surface adjacent to the ulcer to the center of the ulcer. Subsequently the muscularis mucosae extended, and then the submucous coat was repaired. Regeneration of the nerve fibers around the muscularis mucosae seemed to reach its maximum three weeks after irradiation. These proliferating nerves degenerated with deepening of the radiation ulcer, but they were unexpectedly radioresistant and protrude from the surface of the ulcer into the necrotic surrounding tissues. It is concluded that the effect of irradiation on the alleviation of the pain of stomach cancer is not due to the degeneration of the nerves but to elimination of the stimulation of nerves on account of the radiation effect on the cancer cells themselves.

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Abnormal Degeneration
Reactive Hyperemia
Tooth Erosion
Fast Electrons
Gastric Ulcer
Malignant Neoplasm of Stomach
Stomach Carcinoma
Nerve Fibers

About this Paper

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Bone Marrow Neoplasms

Bone Marrow Neoplasms are cancers that occur in the bone marrow. Discover the latest research on Bone Marrow Neoplasms here.

IGA Glomerulonephritis

IgA glomerulonephritis is a chronic form of glomerulonephritis characterized by deposits of predominantly Iimmunoglobin A in the mesangial area. Discover the latest research on IgA glomerulonephritis here.

Cryogenic Electron Microscopy

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

LRRK2 & Immunity During Infection

Mutations in the LRRK2 gene are a risk-factor for developing Parkinson’s disease. However, LRRK2 has been shown to function as a central regulator of vesicular trafficking, infection, immunity, and inflammation. Here is the latest research on the role of this kinase on immunity during infection.

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Meningococcal Myelitis

Meningococcal myelitis is characterized by inflammation and myelin damage to the meninges and spinal cord. Discover the latest research on meningococcal myelitis here.

Alzheimer's Disease: MS4A

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.

Related Papers

Biology Bulletin of the Academy of Sciences of the USSR
V N Mal'tsevN K Evseeva
The American Journal of Digestive Diseases
P H GuthP Foroozan
The American Journal of Physiology
M AltamiranoT C Pérez
Gan no rinsho. Japan journal of cancer clinics
K MarutaM Nishi
© 2020 Meta ULC. All rights reserved