Histological evaluation of the healing potential of the anterior cruciate ligament by means of augmented and non-augmented repair: an in vivo animal study.

Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA
Helmut SeitzThomas Nau

Abstract

The purpose of this animal study was to investigate the healing potential of the anterior cruciate ligament following transaction at the femoral end, by means of both the augmented and the nonaugmented primary repair, focusing on the histological changes during a 12-month postoperative observation period with respect to necrosis and the loss of normal structures during the healing period. Twenty sheep were randomly assigned to nonaugmented primary ACL repair, or to augmented ACL repair using a polyethylene terephthalate (PET) band. At 2, 6, 16, 26 and 52 weeks postoperatively four sheep out of each group were sacrificed. Histological healing was achieved after 16 weeks for the augmented repair group and after 26 weeks for the nonaugmented repair group. The main difference between the two techniques was that the PET augmentation device protected the ligament from necrosis and ligamentization. In this group a consistently normal ligament was seen histologically during the entire postoperative observation period. The nonaugmented repaired ACLs underwent the processes of necrosis and ligamentization.

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Citations

Aug 29, 2013·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Rob P A Janssen, Sven U Scheffler
Feb 5, 2011·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Rob P A JanssenSven U Scheffler
Jul 19, 2013·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Leo PauzenbergerMark Schurz
Feb 4, 2010·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Ashley N MastrangeloMartha M Murray
Mar 24, 2010·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Matthew B FisherSavio L-Y Woo
Mar 4, 2015·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Sai-Chuen FuKai-Ming Chan
Jul 15, 2015·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Samuel A TaylorGregory S DiFelice
Oct 12, 2010·Orthopaedics & Traumatology, Surgery & Research : OTSR·C LöcherbachB Sonnery-Cottet
Aug 8, 2017·The American Journal of Sports Medicine·Carola F van EckNeal S ElAttrache
Aug 20, 2019·British Medical Bulletin·Rocco PapaliaVincenzo Denaro
Jan 7, 2019·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Anne JonkergouwGregory S DiFelice
Sep 16, 2020·The Journal of Bone and Joint Surgery. American Volume·Jonathan D HughesVolker Musahl
Dec 10, 2019·The Knee·Jorge ChahlaMelodie F Metzger
Feb 14, 2021·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Denver A BurtonEvan H Argintar
Mar 9, 2021·Arthroscopy Techniques·Matthew C DaggettAdnan Saithna

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