Histological hair removal study by ruby or alexandrite laser with comparative study on the effects of wavelength and fluence

Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology
Tokue KatoSeiji Kawana

Abstract

Several different laser systems are currently used to remove unwanted hairs. In this study, we studied follicular changes following hair removal with ruby or alexandrite lasers at different fluences. Unwanted hairs were treated with a ruby laser (Chromos 694, ICN PhotonIcs, UK) at 10, 14 or 18 J/cm2 or with an alexandrite laser (LPIR, Cynosure, USA) at 11, 14 or 17 J/cm2. A 3 mm skin punch biopsy was taken immediately after each laser exposure and also 1 month later. Specimens were stained for histological observation. They were observed using immunohistochemistry with antibodies recognizing factor VIII related antigen or PCNA, and also by the TUNEL method. Similarly, electron microscopic observation was examined. Immediately after the laser exposure, moderate follicular damage was observed following treatment with either type of laser. One month later, cystic formation of hair follicles and foreign body giant cells were observed in skin treated with either type of laser. A similar fluence with either laser treatment resulted in similar histological changes. In this study, the histological changes following treatment with a ruby or an alexandrite laser at the same fluence are similar.

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Citations

Sep 1, 2007·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Klaus Sellheyer
Mar 16, 2007·Expert Review of Medical Devices·David J Goldberg
Dec 2, 2011·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Shlomit Halachmi, Moshe Lapidoth
Jan 27, 2010·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Shraddha DesaiIltefat H Hamzavi

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