Histological, histocytochemical and ultrastructural study on the effects of surface charge on bone formation in the rabbit mandible

Archives of Oral Biology
N HamamotoH Ozawa

Abstract

The osteogenic potential of different surface charges was studied by implanting uncharged, negatively changed and positively charged Sephadex beads subperiosteally on the buccal aspect of the mandible. The implant sites were examined 1, 2, and 4 weeks later. New bone formation was observed around the positively charged beads at 2 weeks. An amorphous collagen-free layer seen around the beads consisted of anionic substances and contained needle-like crystals. Tartrate-resistant acid phosphatase-positive, multinucleated giant cells, which had typical fine structural characteristics of osteoclast-like ruffled borders and a clear zone, were observed on the surface of positively charged beads, with osteoblastic cells juxtaposed to them. Bone formation was still going on at 4 weeks in this group. Around the uncharged or negatively charged beads, new bone formation and osteoclast-like cells were not observed at any time. The findings suggest that the surface charge of implant materials has a definite influence on the differentiation of osteoclastic cells and subsequent occurrence of osteoblastic cells leading to formation of bone.

References

May 1, 1990·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·M KrukowskiB L Eppley
Mar 1, 1990·Journal of Biomedical Materials Research·T KokuboT Yamamuro
Feb 1, 1987·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·A A Cole, L M Walters
Sep 1, 1982·Calcified Tissue International·M Krukowski, A J Kahn
Jul 1, 1948·Stain Technology·J F A McMANUS

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Citations

Jul 13, 2002·Journal of Biomedical Materials Research·Satoshi NakamuraKimihiro Yamashita
Aug 16, 2008·Journal of Materials Science. Materials in Medicine·Satoshi NakamuraKimihiro Yamashita
Dec 30, 1999·Biomaterials·D A Puleo, A Nanci
Nov 17, 1999·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·N J TawilT Mustoe
Jul 18, 2014·Colloids and Surfaces. B, Biointerfaces·Niranjan GhimireYing Deng
Feb 19, 1998·Journal of Biomedical Materials Research·J A CobosD J Simmons
Jul 5, 2006·Dental Clinics of North America·David A Puleo, Mark V Thomas

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