Histological Inflammation in Human Ureter either Healthy or Fitted with Double-Pigtail Stent or a Thin 0.3 F Suture Thread: A Preliminary Study

Advances in Urology
Benoît Vogt, Ilham Chokri

Abstract

Ureteral stent intolerance reduces patients' quality of life. It has been suggested that changes in the shape of stents could decrease discomfort. In previous studies, the innovative pigtail-suture stent (i.e., JFil® or MiniJFil®) with a thin 0.3 F suture thread significantly decreased stent-related symptoms. Fortuitously, a dilation of the ureter containing the sutures was discovered. In addition, no inflammation was seen on the ureter wall around the suture in endoscopy. In this preliminary study, we assessed ureteral inflammation in the human ureter when it was healthy or when fitted with a double-pigtail stent or a thread. After consent and inclusion of patients in the protocol, fifteen segments of ureters were collected during cystectomy procedures for bladder tumors. Ureteral inflammation was assessed on the histological section stained with hematoxylin-eosin. Histological grading (cumulative range of 0 to 6) assessing inflammation was performed on the ureter section for mucosa inflammation and inflammation in the muscle layer. A marked ureteral inflammatory reaction was observed in all cases of ureters fitted with a double-pigtail stent with a mean inflammation score of 4.8 ± 0.4. The ureter fitted with the thin suture t...Continue Reading

References

May 28, 2014·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·B VogtF-N Desfemmes
Sep 13, 2014·World Journal of Urology·Benoît VogtFrançois-Noël Desfemmes
Feb 4, 2016·Current Opinion in Urology·Ben H Chew, Dirk Lange

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Citations

Aug 26, 2021·Research and Reports in Urology·Benoît Vogt, Laure-Hélène Blanchet

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Software Mentioned

MiniJFil®

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